Results 201 to 210 of about 316,539 (293)

CNOT3 resists ovarian aging by accelerating oocyte maturation and promoting ESCs differentiation. [PDF]

Stem Cell Res Ther
Li N, Huang E, Wang R, Li J, Yuan X.
europepmc   +1 more source

Selective excitatory effects of γ‐glutamyl‐glycine, a glutathione metabolite, on GluN1 NMDA and mGlu5 receptors impacting synaptic plasticity

British Journal of Pharmacology, EarlyView.
Background and Purpose Gamma‐glutamyl dipeptides are essentially produced after glutathione (GSH) degradation. While several γ‐glutamyl dipeptides have been detected in different organs and body fluids, their biological activity remains elusive. This is the case for γ‐Glutamyl‐Glycine (γ‐Glu‐Gly) which has been found in different brain areas.
Sandro Andreu, Victoria Gizzi, Ugo Pasco, Fatiha Sebih, Yattou Zitouni, Pablo Jimenez, Valérie Rolland, Alain Chavanieu, Sébastien Estaran, Matthieu Rousset, Thierry Cens, Guillaume Cazals, Pierre Charnet, Janique Guiramand, Catherine Cohen‐Solal, Claudine Ménard, Marie‐Céleste de Jésus Ferreira, Nathalie Chevallier, Sonia Cantel, Michel Vignes, Julien Roussel   +20 more
wiley   +1 more source

Ultrastructural Aspects of Oocyte Maturation in Dogs, with Comparative Insights from Cats: Current Evidence and Research Perspectives. [PDF]

Animals (Basel)
Jammula LS, Ochota M, Kulus MJ.
europepmc   +1 more source

Biallelic Truncating Variant in LRGUK Is Associated With Severe Multiple Morphological Abnormalities of the Sperm Flagella and Sperm Nuclear Defects in Humans

Clinical Genetics, EarlyView.
A homozygous truncating variant in LRGUK results in loss of the LRGUK protein and causes multiple morphological abnormalities of the flagella (MMAF), disrupted axonemal architecture, central pair defects, abnormal chromatin organization, and severe male infertility, establishing LRGUK as a novel human infertility gene.
Wiâme Mokkedem, Zeina Wehbe, Anne‐Laure Barbotin, Angèle Boursier, Célia Tebbakh, Nicolas Thierry‐Mieg, Marie Bidart, Antonella Migliaccio, Rosanna Chianese, Christophe Arnoult, Raoudha Zouari, Zine‐Eddine Kherraf, Pierre F. Ray, Guillaume Martinez, Charles Coutton   +14 more
wiley   +1 more source

Acrylamide disrupts meiotic G2/M transition and SAC activity during oocyte maturation. [PDF]

Biol Direct
Chen S, Wang PX, Wang YT, Ke XH, Ou M, Sun SC, Liao BY, Chen X.   +7 more
europepmc   +1 more source

Ploidy‐Dependent Response to Anticancer Drugs of Human Embryonic Stem Cells

Cell Proliferation, EarlyView.
Using isogenic hESCs, differing only in their ploidy level, we show the effect of ploidy on the resistance to anticancer drugs. We demonstrate that polyploidy, by itself, confers sensitivity to chemotherapies, leading to higher apoptosis and delayed proliferation, while the loss of p53 reverses the phenotype, demonstrating higher resistance.
Guy Haim‐Abadi, Nissim Benvenisty
wiley   +1 more source

Impact of mineral oil overlay on immature oocyte maturation in an optimized in vitro culture system. [PDF]

Eur J Med Res
Peng J, Hao Y, Yu Z, Chen B, Zhang Z.
europepmc   +1 more source

Integrating cryobanks into conservation frameworks: The case of boreal caribou in Ontario

Conservation Science and Practice, EarlyView.
Conservation cryobanks are a powerful but underutilized complement to conventional recovery strategies such as habitat protection and population monitoring. Here, we present a transferable, stepwise framework for integrating cryobanking into formal species recovery plans, including guidance on population prioritization, partner engagement, and the ...
Vanessa E. Luzuriaga‐Aveiga, Gregory A. Wilson, Gabriela F. Mastromonaco   +2 more
wiley   +1 more source

Corrigendum to "Mitophagy suggesting a possible association with oocyte maturation: A study of granulosa cells from follicular fluid of normoresponder and diminished ovarian reserve cases". [PDF]

Sci Prog
europepmc   +1 more source