INFLUENCE OF FOLLICULAR MATURATION AND CULTURE CONDITIONS ON THE MEIOSIS OF PIG OOCYTES IN VITRO [PDF]
, 1975 A. Tsafriri, Cornelia P. Channing
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Age‐associated accumulation of RAB9 disrupts oocyte meiosis
Aging Cell, Volume 24, Issue 4, April 2025.This study showed that RAB9 protein accumulates in old human and mouse oocytes. RAB9 accumulation disrupted spindle formation, chromosome alignment and actin cap formation, increased ROS levels, decreased mitochondrial membrane potential, ATP content, mtDNA/nDNA ratio and activated the PINK1‐PARKIN pathway. Importantly, knockdown of RAB9 in old oocytes
Min Gao +10 more
wiley +1 more source
Heat stress affects the functionality of the ovine cumulus-oocyte complex and subsequent in vitro embryo production. [PDF]
Sci RepMartín-Maestro A +7 more
europepmc +1 more source
The action of ethacrynic acid on sodium efflux from single toad oocytes
, 1968 E. Edward Bittar, D. A. T. Dick, D. Fry
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Determination of the nucleoside triphosphate contents of eggs and oocytes of Xenopus laevis [PDF]
, 1972 Hugh R. Woodland, R. Q. W. Pestell
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CALB1 and RPL23 Are Essential for Maintaining Oocyte Quality and Function During Aging
Aging Cell, Volume 24, Issue 5, May 2025.This study investigates the mechanisms of oocyte aging in mice, identifying Calb1 and Rpl23 as key genes involved in calcium ion homeostasis and mitochondrial function. Knockdown of these genes led to mitochondrial dysfunction, meiotic defects, and spindle assembly abnormalities, while their overexpression partially rescued age‐related oocyte defects ...
Yingxue Han +6 more
wiley +1 more source
<i>DLGAP5</i> mutations Disrupt Normal Chromosome Segregation and Spindle Formation of human Oocyte Meiosis and Lead to Female Infertility. [PDF]
MedComm (2020)Wang M +8 more
europepmc +1 more source
Fine Morphology of Human Oocyte Maturation In Vitro12 [PDF]
, 1972 L Zamboni +2 more
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Salidroside Improves Oocyte Competence of Reproductively Old Mice by Enhancing Mitophagy
Aging Cell, Volume 24, Issue 5, May 2025.Salidroside improves oocyte competence by enhancing mitophagy. Aging impairs mitophagy in oocytes, which leads to mitochondrial dysfunction. Salidroside restores mitochondrial homeostasis, reduces ROS levels, and improves oocyte developmental competence.
Jingkai Gu +9 more
wiley +1 more source