Results 61 to 70 of about 299,479 (314)

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

open access: yesAdvanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou   +10 more
wiley   +1 more source

Relationships among tissues, biofluids, and otolith selenium concentrations in wild female burbot (Lota lota)

open access: yesIntegrated Environmental Assessment and Management, EarlyView., 2023
Abstract In the Lake Koocanusa‐Kootenai River system (Montana, USA and British Columbia, Canada), selenium (Se) contamination has become an international concern and is suspected to contribute to the observed burbot (Lota lota) population collapse. Due to our limited ability to sample burbot in Lake Koocanusa for monitoring studies, we used a reference
Stephanie D. Graves   +6 more
wiley   +1 more source

Effect of Liquid Marble 3D Culture System on In Vitro Maturation and Embryo Development of Prepubertal Goat Oocytes

open access: yesAnimals
Suboptimal culture conditions during in vitro maturation (IVM) affect oocyte developmental competence and the viability of the resulting embryo. Three-dimensional (3D) culture systems provide a more biologically appropriate environment compared to ...
Andrea Podda   +6 more
doaj   +1 more source

Etude de la fécondité du silure Africain Heterobranchus bidorsalis (Geoffroy Saint-Hilaire, 1840) en conditions d'élevage [PDF]

open access: yesTropicultura, 2010
Artificial Reproduction and Fecundity of the African Catfish Heterobranchus bidorsalis (Geoffroy Saint- Hilaire, 1840). Through the artificial reproduction of Heterobranchus bidorsalis, fecundity of females, characteristics of oocytes and larvae after ...
Alla, YL.   +3 more
doaj  

Implications of storage and handling conditions on glass transition and potential devitrification of oocytes and embryos [PDF]

open access: yes, 2014
Devitrification, the process of crystallization of a formerly crystal-free, amorphous glass state, can lead to damage during the warming of cells.
Sansinena, Marina Julia   +3 more
core   +1 more source

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

open access: yesAdvanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li   +11 more
wiley   +1 more source

Reproductive biology of blue marlin (Makaira nigricans) in the western Pacific Ocean [PDF]

open access: yes, 2009
The reproductive biology of blue marlin (Makaira nigricans) was assessed from 1001 fish (ranging from 121 to 275 cm in eye-to-fork length; EFL) caught by Taiwanese offshore longliners in the western Pacific Ocean from September 2000 to December ...
Chien-Chung Tszeng, Chien-Chung Tszeng   +3 more
core  

CO2 per se activates carbon dioxide receptors. [PDF]

open access: yes, 2020
Carbon dioxide has been used in traps for more than six decades to monitor mosquito populations and help make informed vector management decisions. CO2 is sensed by gustatory receptors (GRs) housed in neurons in the maxillary palps.
Leal, Walter S, Wen, Xiaolan, Xu, Pingxi
core   +1 more source

Depletion of Sorcs3 Activates Totipotency in Mouse Embryonic Stem Cells by Modulating Key Signaling Pathways

open access: yesAdvanced Science, EarlyView.
In this article, Shuai and colleagues found that depletion of Sorcs3 could activate totipotency in mESCs, promising bidirectional differentiation potential to embryonic and extraembryonic lineages. The underlying mechanism might be activation of Tfap2c and repression of TGF‐β, PI3K‐AKT, and lysosome pathways.
Wenhao Zhang   +12 more
wiley   +1 more source

In vitro maturation of collared peccary (Pecari tajacu) oocytes after different incubation times

open access: yesPesquisa Veterinária Brasileira
: Oocyte in vitro maturation (IVM) is the first step of the in vitro reproductive technologies that enables mature oocytes to be generated ex vivo and after used for embryo production.
Alana A. Borges   +5 more
doaj   +1 more source

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