Results 21 to 30 of about 36,504 (227)

Ablation of the MiR-17-92 MicroRNA Cluster in Germ Cells Causes Subfertility in Female Mice

Cellular Physiology and Biochemistry, 2018
Background/Aims: Oogenesis is a highly complex process that is intricately regulated by interactions of multiple genes and signaling molecules. However, the underlying molecular mechanisms are poorly understood.
Jian Wang, Bo Xu, Geng G. Tian, Tao Sun, Ji Wu   +4 more
doaj   +1 more source

Single-Cell Atlas of the Chinese Tongue Sole (Cynoglossus semilaevis) Ovary Reveals Transcriptional Programs of Oogenesis in Fish

Frontiers in Cell and Developmental Biology, 2022
Oogenesis is a highly orchestrated process that depends on regulation by autocrine/paracrine hormones and growth factors. However, many details of the molecular mechanisms that regulate fish oogenesis remain elusive.
Xiang Liu, Xiang Liu, Yingyi Huang, Yingyi Huang, Fujian Tan, Fujian Tan, Hong-Yan Wang, Hong-Yan Wang, Jian-Yang Chen, Jian-Yang Chen, Jian-Yang Chen, Xianghui Zhang, Xianghui Zhang, Xiaona Zhao, Xiaona Zhao, Kaiqiang Liu, Kaiqiang Liu, Qian Wang, Qian Wang, Shanshan Liu, Shanshan Liu, Shanshan Liu, Francesc Piferrer, Guangyi Fan, Guangyi Fan, Changwei Shao, Changwei Shao   +26 more
doaj   +1 more source

High-dose irradiation induces cell cycle arrest, apoptosis, and developmental defects during Drosophila oogenesis. [PDF]

PLoS ONE, 2014
Ionizing radiation (IR) treatment induces a DNA damage response, including cell cycle arrest, DNA repair, and apoptosis in metazoan somatic cells. Because little has been reported in germline cells, we performed a temporal analysis of the DNA damage ...
Hee Jin Shim, Eun-Mi Lee, Long Duy Nguyen, Jaekyung Shim, Young-Han Song   +4 more
doaj   +1 more source

Murder on the Ovarian Express: A Tale of Non-Autonomous Cell Death in the Drosophila Ovary

Cells, 2021
Throughout oogenesis, Drosophila egg chambers traverse the fine line between survival and death. After surviving the ten early and middle stages of oogenesis, egg chambers drastically change their size and structure to produce fully developed oocytes ...
Diane Patricia Vig Lebo, Kimberly McCall
doaj   +1 more source

foxl3, a sexual switch in germ cells, initiates two independent molecular pathways for commitment to oogenesis in medaka

Proceedings of the National Academy of Sciences of the United States of America, 2020
Significance In teleost fish, unlike mammals, retinoic acid (RA) does not exert a conspicuous feminization effect of germ cells. Instead, in the teleost fish medaka, foxl3 serves as a germ cell-autonomous factor acting at the very beginning of the sexual
Mariko Kikuchi, T. Nishimura, S. Ishishita, Y. Matsuda, Minoru Tanaka   +4 more
semanticscholar   +1 more source

Generation and Characterization of Germline-Specific Autophagy and Mitochondrial Reactive Oxygen Species Reporters in Drosophila

Frontiers in Cell and Developmental Biology, 2019
Oogenesis is a fundamental process that forms the egg and, is crucial for the transmission of genetic information to the next generation. Drosophila oogenesis has been used extensively as a genetically tractable model to study organogenesis, niche ...
Kiran Nilangekar, Kiran Nilangekar, Nidhi Murmu, Nidhi Murmu, Govind Sahu, Bhupendra V. Shravage, Bhupendra V. Shravage   +6 more
doaj   +1 more source

Juvenile hormone signaling in insect oogenesis.

Current Opinion in Insect Science, 2019
Juvenile hormone (JH) plays a crucial role in insect reproduction, but its molecular mode of action only became clear within the last decade. We here review recent findings revealing the intricate crosstalk between JH and ecdysone signaling with nutrient
Carolina G. Santos, F. C. Humann, K. Hartfelder   +2 more
semanticscholar   +1 more source

Sexual and asexual oogenesis require the expression of unique and shared sets of genes in the insect Acyrthosiphon pisum

BMC Genomics, 2012
Background Although sexual reproduction is dominant within eukaryotes, asexual reproduction is widespread and has evolved independently as a derived trait in almost all major taxa. How asexuality evolved in sexual organisms is unclear.
Gallot Aurore, Shigenobu Shuji, Hashiyama Tomomi, Jaubert-Possamai Stéphanie, Tagu Denis   +4 more
doaj   +1 more source

E-cadherin acts as a positive regulator of the JAK-STAT signaling pathway during Drosophila oogenesis

Frontiers in Cell and Developmental Biology, 2022
The JAK-STAT pathway is evolutionary conserved. The simplicity of this signaling in Drosophila, due to the limited redundancy between pathway components, makes it an ideal model for investigation.
Charlotte Mallart, Fabienne Chalvet, Sophie Netter, Alba Yurani Torres, Mickael Poidevin, Jacques Montagne, Anne-Marie Pret, Marianne Malartre   +7 more
doaj   +1 more source

A developmental stage-specific switch from DAZL to BOLL occurs during fetal oogenesis in humans, but not mice.

PLoS ONE, 2013
The Deleted in Azoospermia gene family encodes three germ cell-specific RNA-binding proteins (DAZ, DAZL and BOLL) that are essential for gametogenesis in diverse species.
Jing He, Kayleigh Stewart, Hazel L Kinnell, Richard A Anderson, Andrew J Childs   +4 more
doaj   +1 more source