Results 51 to 60 of about 2,537 (171)

Outpatient Parenteral Antimicrobial Therapy in Pediatric Patients

open access: yesJournal of Behçet Uz Children's Hospital
Objective: Outpatient parenteral antimicrobial therapy (OPAT) has been developed as an alternative approach to hospital stay for the effective treatment of infections requiring long-term therapy. The aim of this study is to evaluate the clinical outcomes
Hıncal Özbakır   +10 more
doaj   +1 more source

Body Mass Index and Clinical Associations in Australasian Lymphoma Patients: A Lymphoma and Related Diseases Registry Study

open access: yeseJHaem, Volume 7, Issue 2, April 2026.
ABSTRACT Introduction Overweight and obesity are increasing rapidly in most countries. Underweight body mass index (BMI), though much less common, is also associated with adverse health outcomes. There is poor understanding of the implications of BMI in lymphoma patients.
Serif Sungur   +14 more
wiley   +1 more source

The OPAT opportunity for beta-lactam individualization

open access: yesAntimicrobial Stewardship & Healthcare Epidemiology
Abstract Beta-lactam therapeutic drug monitoring has been growing in prevalence in the acute care hospital setting. Expansion of its use to outpatient parenteral antimicrobial therapy requires careful consideration of potential logistical and therapeutic barriers.
Lindsey M. Childs-Kean   +4 more
openaire   +3 more sources

X‐Ray Tomography Analysis of Damage Mechanisms in Metal Matrix Syntactic Foams During Compression

open access: yesAdvanced Engineering Materials, Volume 28, Issue 3, 4 February 2026.
In situ synchrotron X‐ray tomography is used to investigate the internal damage mechanisms of AlSi12 metal matrix syntactic foam with ceramic hollow spheres during compressive loading. It is concluded that a homogeneous distribution of the second‐phase filler material results in a sequential collapse in a localized region; this leads to controlled and ...
Indrajeet Tambe   +8 more
wiley   +1 more source

341 Implementation of an Antimicrobial Stewardship Program in a Private Hospital: Clinical, Microbiological, and Economic Outcomes

open access: yesAntimicrobial Stewardship & Healthcare Epidemiology
Background: Outpatient parenteral antimicrobial therapy (OPAT) is a common approach to treating complex infections, offering benefits of higher patient satisfaction, reduced risk of hospital-acquired infections, and lower healthcare costs.
Manon Nitta   +11 more
doaj   +1 more source

Patient outcomes following home-based outpatient parenteral antimicrobial therapy and facility-based outpatient parenteral antimicrobial therapy: a systematic review and meta-analysis

open access: yesAntimicrobial Stewardship & Healthcare Epidemiology, 2023
In this systematic literature review and meta-analysis, we did not find a statistically significant difference in readmission and treatment failure rates between home-based and facility-based OPAT.
Shinya Hasegawa   +3 more
doaj   +1 more source

Cost‐Effectiveness of Once Weekly Rezafungin for the Treatment of Invasive Candidiasis in the United Kingdom

open access: yesMycoses, Volume 69, Issue 2, February 2026.
ABSTRACT Background Invasive candidiasis (IC), life‐threatening fungal infections with high economic burden, are often treated first‐line with daily intravenous echinocandins. A new once weekly echinocandin, rezafungin, demonstrated statistically non‐inferior efficacy and numerically shorter intensive care unit (ICU) stay compared to caspofungin in ...
Noemi Muszbek   +10 more
wiley   +1 more source

Conventional Hospitalization versus Sequential Outpatient Parenteral Antibiotic Therapy for Staphylococcus aureus Bacteremia: Post-Hoc Analysis of a Multicenter Observational Cohort

open access: yesAntibiotics, 2023
It is not known whether sequential outpatient parenteral antimicrobial (OPAT) is as safe and effective as conventional hospitalization in patients with S. aureus bacteremia (SAB).
Nerea Castillo-Fernández   +27 more
doaj   +1 more source

Rezafungin for Salvage or Consolidation Therapy of Invasive Fungal Disease: Experience in Real‐World Clinical Practice

open access: yesMycoses, Volume 69, Issue 2, February 2026.
ABSTRACT Background Echinocandins are the first‐line treatment for invasive candidiasis. Rezafungin is a novel echinocandin with improved pharmacokinetic properties that allow for once‐weekly intravenous administration, offering potential advantages in complex clinical settings.
Jorge Boán   +10 more
wiley   +1 more source

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