Results 41 to 50 of about 76,590 (291)
, 2016 Open-angle glaucoma (OAG) is an important cause of irreversible blindness. In OAG, loss of retinal ganglion cells leads to damage of the optic nerve. This causes visual field loss and eventually blindness.
Springelkamp, H. (Henriët)
core
Evaluation of the progression of visual field damage in patients suffering from early manifest glaucoma [PDF]
, 2016 BACKGROUND: This retrospective study aimed to determine how often a perimetric examination should be carried out in order to identify visual field (VF) changes in patients with relatively early manifestation glaucoma.
Abdolrahimzadeh, S +4 more
core +1 more source
Advanced Science, EarlyView.Microglial lipid metabolic dysfunction drives neurodegeneration in glaucoma. We found loss of LRP1 causes lipid accumulation and inflammation. We developed alpinetin‐loaded nanoparticles (AlpNPs) that bind LRP1, activate the PPARγ‐LXRα‐ABCA1 pathway to restore lipid homeostasis, promote an anti‐inflammatory phenotype, and protect retinal ganglion cells,
Miao Wei +8 more
wiley +1 more source
Neuroinflammation in Primary Open-Angle Glaucoma [PDF]
Journal of Clinical Medicine, 2020 Primary open-angle glaucoma (POAG) is the second leading cause of irreversible blindness worldwide. Increasing evidence suggests oxidative damage and immune response defects are key factors contributing to glaucoma onset. Indeed, both the failure of the trabecular meshwork tissue in the conventional outflow pathway and the neuroinflammation process ...
Stefania Vernazza +4 more
openaire +2 more sources
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Noonan Syndrome (NS) is a clinically and genetically heterogeneous condition characterized by typical facial dysmorphisms, short stature, congenital heart defects, and developmental delays. While variants in genes such as PTPN11, SOS1, and RAF1 account for most genetically confirmed cases, diagnosis is challenging due to phenotypic overlap ...
Gabriela Jeesoo Kim +9 more
wiley +1 more source
Corneal alterations associated with pseudoexfoliation syndrome and glaucoma: A literature review [PDF]
, 2017 A systematic literature review was performed evaluating articles examining the effects of pseudoexfoliation syndrome (PEX) and glaucoma (PEXG) on the cornea with a focus on the corneal endothelium.
Palko, Joel R +2 more
core +7 more sources
Pharmacogenetics of ophthalmic topical β-blockers [PDF]
, 2008 Glaucoma is the second leading cause of blindness worldwide. The primary glaucoma risk factor is elevated intraocular pressure. Topical β-blockers are affordable and widely used to lower intraocular pressure.
McCarty, Catherine A. +4 more
core +1 more source
Mechanochromic Organic Materials: Molecular Mechanisms and Multidimensional Applications
Advanced Physics Research, EarlyView.Mechanochromic (MC) organic materials change color in response to mechanical force. This review elucidates the molecular mechanisms (e.g., aggregation‐induced emission, AIE) and explores their multidimensional applications in sensors, anti‐counterfeiting, biomedical devices, and structural health monitoring, providing a roadmap for future smart ...
Xiaozhe Yin +5 more
wiley +1 more source
Pseudoexfoliative Syndrome and Pseudoexfoliative Glaucoma in Primorsko-Goranska County [PDF]
, 2010 The aim of this study is to evaluate pseudoexfoliative glaucoma (PEX) in Primorsko-Goranska County, Croatia, and its characteristics comparing to primary open angle glaucoma (POAG).
Damir Kovačević +3 more
core +1 more source
Glaucoma and cigarette smoking: a review of narrative reviews [PDF]
, 2016 Background: Glaucoma is an optic neuropathy associated with visual field changes for which high intra-ocular pressure is a major risk factor. Emerging research indicates that modifiable factors, among which the cigarette smoke, besides IOP may be ...
DI MURRO, FRANCESCA +3 more
core +2 more sources