Results 61 to 70 of about 1,102,129 (260)
Speckle observations of binary stars with a 0.5 m telescope
We present 36 observations of 17 visual binaries of moderate separation (range from 0.15'' to 0.79'') made with the 50 cm Cassegrain telescope of the Jagiellonian University in Cracow. The speckle interferometry technique was combined with modest optical
Rutkowski, Artur, Waniak, Waclaw
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
A novel method for fault diagnosis for rolling bearing of wind turbine based on combining morphological filter and ensemble empirical mode decomposition(EEMD)is presented.Firstly,de-noising processing of the practical bearing fault signal is carried out ...
宗永涛 +3 more
doaj
Data-Driven Tight Frame for Cryo-EM Image Denoising and Conformational Classification
The cryo-electron microscope (cryo-EM) is increasingly popular these years. It helps to uncover the biological structures and functions of macromolecules. In this paper, we address image denoising problem in cryo-EM. Denoising the cryo-EM images can help
Cai, Jian-Feng +6 more
core +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Design of Acoustic Equalization Filters for Headphones Based on Low-Rank Regularization
The use of equalization filters to achieve acoustic transparency can improve the sound quality of hearables and hearing aids. Finite impulse response (FIR) filters guarantee stability and offer a listening impression close to the open ear, but their ...
Florian Hilgemann, Peter Jax
doaj +1 more source
Helical coaxial resonator RF filter [PDF]
Helical coaxial resonator RF ...
Maxwell, M. W.
core +1 more source
Flat zones filtering, connected operators, and filters by reconstruction [PDF]
This correspondence deals with the notion of connected operators. Starting from the definition for operator acting on sets, it is shown how to extend it to operators acting on function.
Salembier Clairon, Philippe Jean +1 more
core +2 more sources
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source

