Results 61 to 70 of about 1,102,129 (260)

Speckle observations of binary stars with a 0.5 m telescope

open access: yes, 2005
We present 36 observations of 17 visual binaries of moderate separation (range from 0.15'' to 0.79'') made with the 50 cm Cassegrain telescope of the Jagiellonian University in Cracow. The speckle interferometry technique was combined with modest optical
Rutkowski, Artur, Waniak, Waclaw
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

基于形态学滤波和EEMD方法的风力发电系统滚动轴承故障诊断

open access: yesJixie chuandong, 2014
A novel method for fault diagnosis for rolling bearing of wind turbine based on combining morphological filter and ensemble empirical mode decomposition(EEMD)is presented.Firstly,de-noising processing of the practical bearing fault signal is carried out ...
宗永涛   +3 more
doaj  

Data-Driven Tight Frame for Cryo-EM Image Denoising and Conformational Classification

open access: yes, 2018
The cryo-electron microscope (cryo-EM) is increasingly popular these years. It helps to uncover the biological structures and functions of macromolecules. In this paper, we address image denoising problem in cryo-EM. Denoising the cryo-EM images can help
Cai, Jian-Feng   +6 more
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Design of Acoustic Equalization Filters for Headphones Based on Low-Rank Regularization

open access: yesIEEE Open Journal of Signal Processing
The use of equalization filters to achieve acoustic transparency can improve the sound quality of hearables and hearing aids. Finite impulse response (FIR) filters guarantee stability and offer a listening impression close to the open ear, but their ...
Florian Hilgemann, Peter Jax
doaj   +1 more source

Helical coaxial resonator RF filter [PDF]

open access: yes, 1969
Helical coaxial resonator RF ...
Maxwell, M. W.
core   +1 more source

Flat zones filtering, connected operators, and filters by reconstruction [PDF]

open access: yes, 1995
This correspondence deals with the notion of connected operators. Starting from the definition for operator acting on sets, it is shown how to extend it to operators acting on function.
Salembier Clairon, Philippe Jean   +1 more
core   +2 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy