Results 51 to 60 of about 156,017 (326)

Can Observational Learning Reinforce Open-label Placebo Hypoalgesia?

Pain, 2023
Previous research has indicated that an open-label placebo can reduce pain in both healthy participants and chronic pain patients. As nondeceptive placebos seem to be an effective and more ethical alternative to deceptive placebos, optimizing this kind of treatment is essential.
Justyna Brączyk, Przemysław Bąbel
openaire   +3 more sources

The health economic potential of harnessing placebos in treatment of ADHD

European Psychiatry, 2021
Introduction Placebo research investigated the underlying mechanisms of placebo effects, but they are rarely used to optimize treatments. Ethical and legal concerns have been raised, but research demonstrated that placebo mechanisms can be used without
J. Hamberger, K. Meissner, T. Hinterberger, T. Loew   +3 more
doaj   +1 more source

Evidencing general acceptability of open-label placebo use for tackling overtreatment in primary care: a mixed methods study

BMC Medicine, 2023
Background Overtreatment poses a challenge to healthcare systems due to harmful consequences of avoidable side-effects and costs. This study presents the first account for examining the feasibility of placebo use for reducing overtreatment in primary ...
E. M. Krockow, T. Emerson, E. Youssef, S. Scott, S. Tromans   +4 more
doaj   +1 more source

Open-Label Placebo Interventions With Drinking Water and Their Influence on Perceived Physical and Mental Well-Being

Frontiers in Psychology, 2021
In recent years, the postulation that deception is necessary for placebos to have an effect on pain relief or increased well-being has come into question. Latest studies have shown that an openly administered mock drug works just as well as a deceptively
Marco Rathschlag, Stefanie Klatt, Stefanie Klatt, Stefanie Klatt   +3 more
doaj   +1 more source

Placebo Effects of Open-label Verbal Suggestions on Itch [PDF]

Acta Dermato Venereologica, 2018
Placebo effects are positive outcomes that are not due to active treatment components, which may be elicited even when patients are aware of receiving an inert substance (open-label). This proof-of-principle study investigated for the first time whether open-label placebo effects on itch can be induced by verbal suggestions alone.
Meeuwis, S.H., van Middendorp, H., van Middendorp, H., Veldhuijzen, D.S., van Laarhoven, A.I.M., van Laarhoven, A.I.M., de Houwer, J., Lavrijsen, A.P.M., Evers, A.W.M., Evers, A.W.M.   +9 more
openaire   +6 more sources

Informed consent and placebo effects: a content analysis of information leaflets to identify what clinical trial participants are told about placebos [PDF]

, 2012
BackgroundPlacebo groups are used in randomised clinical trials (RCTs) to control for placebo effects, which can be large. Participants in trials can misunderstand written information particularly regarding technical aspects of trial design such as ...
Adams, Alison E.M., Bishop, Felicity L., Kaptchuk, Ted J., Lewith, George   +3 more
core   +5 more sources

Placebos without deception: a randomized controlled trial in irritable bowel syndrome. [PDF]

PLoS ONE, 2010
Placebo treatment can significantly influence subjective symptoms. However, it is widely believed that response to placebo requires concealment or deception.
Ted J Kaptchuk, Elizabeth Friedlander, John M Kelley, M Norma Sanchez, Efi Kokkotou, Joyce P Singer, Magda Kowalczykowski, Franklin G Miller, Irving Kirsch, Anthony J Lembo   +9 more
doaj   +1 more source

Relieving pain using dose-extending placebos [PDF]

, 2016
Placebos are often used by clinicians, usually deceptively and with little rationale or evidence of benefit, making their use ethically problematic. In contrast with their typical current use, a provocative line of research suggests that placebos can be ...
Colloca, Luana, DeGrazia, David, Enck, Paul   +2 more
core   +1 more source

Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis. [PDF]

, 2004
BACKGROUND: An open-label study indicated that selective depletion of B cells with the use of rituximab led to sustained clinical improvements for patients with rheumatoid arthritis. To confirm these observations, we conducted a randomized, double-blind,
Close, DR, Edwards, JCW, Emery, P, Filipowicz-Sosnowska, A, Shaw, T, Stevens, RM, Szczepanski, L, Szechinski, J   +7 more
core   +1 more source

The roles of expectation, comparator, administration route, and population in open-label placebo effects: a network meta-analysis

Scientific Reports, 2023
Three meta-analyses have demonstrated the clinical potential of open-label placebos (OLPs). However, there is a need to synthesize the existing evidence through more complex analyses that would make it possible to answer questions beyond mere efficacy ...
Sarah Buergler, Dilan Sezer, J. Gaab, Cosima Locher   +3 more
semanticscholar   +1 more source