Results 121 to 130 of about 522,323 (249)

Advanced Experiment Design Strategies for Drug Development

Advanced Intelligent Discovery, EarlyView.
Wang et al. analyze 592 drug development studies published between 2020 and 2024 that applied design of experiments methodologies. The review surveys both classical and emerging approaches—including Bayesian optimization and active learning—and identifies a critical gap between advanced experimental strategies and their practical adoption in ...
Fanjin Wang, Anthony Harker, Mohan Edirisinghe, Maryam Parhizkar   +3 more
wiley   +1 more source

Augmenting large language models to predict social determinants of mental health in opioid use disorder using patient clinical notes. [PDF]

JAMIA Open
Pagare M, Bheesetti DSK, Essien-Aleksi I, Alam MAU.   +3 more
europepmc   +1 more source

Toward Knowledge‐Guided AI for Inverse Design in Manufacturing: A Perspective on Domain, Physics, and Human–AI Synergy

Advanced Intelligent Discovery, EarlyView.
This perspective highlights how knowledge‐guided artificial intelligence can address key challenges in manufacturing inverse design, including high‐dimensional search spaces, limited data, and process constraints. It focused on three complementary pillars—expert‐guided problem definition, physics‐informed machine learning, and large language model ...
Hugon Lee, Hyeonbin Moon, Junhyeong Lee, Seunghwa Ryu   +3 more
wiley   +1 more source

An Integrated Cyber-Physical Digital Twin Architecture with Quantitative Feedback Theory Robust Control for NIS2-Aligned Industrial Robotics. [PDF]

Sensors (Basel)
Karlova-Sergieva V, Grasiani B, Nikolova N.   +2 more
europepmc   +1 more source

Toward Predictable Nanomedicine: Current Forecasting Frameworks for Nanoparticle–Biology Interactions

Advanced Intelligent Discovery, EarlyView.
Predictive models successfully screen nanoparticles for toxicity and cellular uptake. Yet, complex biological dynamics and sparse, nonstandardized data limit their accuracy. The field urgently needs integrated artificial intelligence/machine learning, systems biology, and open‐access data protocols to bridge the gap between materials science and safe ...
Mariya L. Ivanova, Michael Nicholls, Nicola Russo, Gueorgui Mihaylov, Konstantin Nikolic   +4 more
wiley   +1 more source

Strangulated Adhesive Internal Hernia in a Virgin Abdomen: A Rare Cause of Closed-Loop Obstruction in an Elderly Patient - A Case Report. [PDF]

Clin Med Insights Case Rep
Farhat H, Nasr R, Khalifeh G.
europepmc   +1 more source

A Review on Recent Trends of Bioinspired Soft Robotics: Actuators, Control Methods, Materials Selection, Sensors, Challenges, and Future Prospects

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
This article reviews the current state of bioinspired soft robotics. The article discusses soft actuators, soft sensors, materials selection, and control methods used in bioinspired soft robotics. It also highlights the challenges and future prospects of this field.
Abhirup Sarker, Tamzid Ul Islam, Md. Robiul Islam   +2 more
wiley   +1 more source

Implementation pathways of a health services delivery redesign model to improve maternal and newborn outcomes in Kenya. [PDF]

BMJ Glob Health
Chen M, Ji T, Wedlock PT, Bwire V, Nyanchama E, Angote Mbelesia J, Wandei S, Kalbarczyk A, Nimako K, Subramanian S, Peters DH, Igusa T, Alonge O.   +12 more
europepmc   +1 more source

Multiobjective Environmental Cleanup with Autonomous Surface Vehicle Fleets Using Multitask Multiagent Deep Reinforcement Learning

Advanced Intelligent Systems, EarlyView.
This study presents a multitask strategy for plastic cleanup with autonomous surface vehicles, combining exploration and cleaning phases. A two‐headed Deep Q‐Network shared by all agents is traineded via multiobjective reinforcement learning, producing a Pareto front of trade‐offs.
Dame Seck, Samuel Yanes, Manuel Perales, Daniel Gutiérrez, Sergio Toral   +4 more
wiley   +1 more source

Microendovascular Neural Recording from Cortical and Deep Vessels with High Precision and Minimal Invasiveness

Advanced Intelligent Systems, EarlyView.
Intravascular electroencephalography (ivEEG) using micro‐intravascular electrodes was developed. Cortical‐vein ivEEG showed a higher signal‐to‐noise ratio and finer spatial resolution of somatosensory evoked potentials (SEPs) than superior sagittal sinus ivEEG, and deep‐vein ivEEG captured clear visual evoked potentials.
Takamitsu Iwata, Hajime Nakamura, Takafumi Uemura, Teppei Araki, Takaki Matsumura, Takaaki Abe, Toshikazu Nezu, Masatoshi Takagaki, Tomohiko Ozaki, Shinpei Miura, Ryohei Fukuma, Sam E. John, David B. Grayden, Haruhiko Kishima, Tsuyoshi Sekitani, Takufumi Yanagisawa   +15 more
wiley   +1 more source