Results 221 to 230 of about 391,445 (269)

Co‐Opting MBNL‐Dependent Alternative Splicing Cassette Exons to Control Gene Therapy in Myotonic Dystrophy

Annals of Neurology, EarlyView.
Objective Myotonic dystrophy type 1 (DM1) is a highly variable, multisystemic genetic disorder caused by a CTG repeat expansion in the 3′ untranslated region of DMPK. Toxicity is exerted by repeat‐containing DMPK transcripts that sequester muscleblind‐like (MBNL) proteins and lead to deleterious yet predictable changes in alternative splicing.
Samuel T. Carrell, Ellie M. Carrell, Ryan Giovenco, Beverly L. Davidson   +3 more
wiley   +1 more source

Augmenting large language models to predict social determinants of mental health in opioid use disorder using patient clinical notes. [PDF]

JAMIA Open
Pagare M, Bheesetti DSK, Essien-Aleksi I, Alam MAU.   +3 more
europepmc   +1 more source

Intraoperative diagnosis of Amyand's hernia: inguinal herniorrhaphy, appendicectomy and orchidectomy. [PDF]

BMJ Case Rep
Rickward H, Karnik VA, Dissanayake T.
europepmc   +1 more source

Global health burdens of plastics: a lifecycle assessment model from 2016 to 2040.

Lancet Planet Health
Deeney M, Hamelin L, Vialle C, Yan X, Green R, Yates J, Kadiyala S.   +6 more
europepmc   +1 more source

A novel targeting domain directs essential components of the cytosolic iron-sulfur cluster assembly pathway to the mitochondrion of Toxoplasma parasites. [PDF]

PLoS Biol
Hodgson ER, Hayward JA, Leonard RA, Makota FV, van Dooren GG.   +4 more
europepmc   +1 more source

Integrated Evaluation of Contaminant Profiles, Detection Techniques, and Management Strategies for Tannery Sludge

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT This review article critically examines the environmental and health hazards of tannery sludge (TS), a complex by‐product of the leather tanning industry. TS is characterized by a diverse array of contaminants, including heavy metals like chromium, organic pollutants such as polycyclic aromatic hydrocarbons (PAHs), volatile organic compounds ...
Yashar Aryanfar, Ali Keçebaş, Soheil Hassanzadeh, Arash Nourbakhsh Sadabad, Farhan Lafta Rashid, Shabbir Ahmad, Ahmed Hendy, Hafiz M. Irfan, Shaban Mousavi Ghasemlou, Julio Blanco Fernandez, Jorge Luis Garcia Alcaraz   +10 more
wiley   +1 more source

The necessity of multimodal feedback for learning effective pedagogical policies with reinforcement learning. [PDF]

Sci Rep
Che L, Guo P, Isleem HF, Wang Z.
europepmc   +1 more source

LCMSpector: A simple open-source viewer for targeted hyphenated mass spectrometry analysis. [PDF]

PLoS Comput Biol
Fido M, Hoesli E, Barazzone EC, Zenobi R, Slack E.   +4 more
europepmc   +1 more source

Advancing the use of artificial intelligence in health technology assessment activities: insights and next steps from the 2025 HTAi Global Policy Forum. [PDF]

Int J Technol Assess Health Care
Trowman R, Boysen M, Migliore A, Valiotis G.   +3 more
europepmc   +1 more source