Results 61 to 70 of about 16,102,303 (245)
, 2022 Date scanned: 2002-7-16.Figure 8 Open pit uranium mine Zee-3. Outlined area "B" of figure 5.Held in the Russell L. and Lyn Wood Mining History Archive, Arthur Lakes Library, Colorado School of Mines.Donor: United States Bureau of Mines.An image of the ...
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Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Lignite price negotiation between opencast mine and power plant as a two-stage, two-person, cooperative, non-zero sum game [PDF]
Based on the simple model of the deposit the methodology of finding the optimal solution for bilateral monopoly (BM) of lignite mine and power plant is shown taking into account pit optimisation.
Jurdziak, Leszek
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Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Strategies for automating open pit mine haulage planning
, 2003 The traditional approach to open pit mine planning has consisted of an iterative process of economic modeling, pit limit determination, pushback design and production scheduling. Even though truck haulage costs typically account for one-third to one-half
Bush, Terry Alan
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DronesWith the advancement of drone technology, the availability of different sensors has become more reliable and cost-effective for monitoring large open-pit mine project activities.
Kapoor Chand +6 more
doaj +1 more source
, 2022 #11; Evergreen Mines Company, Alice Mine. Area of blast seen in No. 7. Eveleth, Minnesota. - October 1941.Date scanned: 2002-6-12.Held in the Russell L.
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Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source