Results 71 to 80 of about 53,082 (303)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Physical model test study on shear strength characteristics of slope sliding surface in Nanfen open-pit mine

, 2020
A physical model for the footwall slope of Nanfen open-pit mine, China was established using a self-developed deep geological engineering disaster model test system. A thermosensitive similar material, paraffin, was selected to simulate a weak structural
Z. Tao, Yuxuan Shu, Xiaojie Yang, Yanyan Peng, Qihang Chen, Haijiang Zhang   +5 more
semanticscholar   +1 more source

Landslide mechanism and stability of an open-pit slope: The Manglai open-pit coal mine

Frontiers in Earth Science, 2023
A clear understanding of landslide mechanisms and stability analyses is of great significance for landslide monitoring, prediction, and control. A large-scale end wall landslide occurred and its area reached 47,752 m2 on August 7–20, 2020, in the Manglai
Tao Chen, Jisen Shu, Liu Han, Gerson S. V. Tovele, Bao-sheng Li   +4 more
semanticscholar   +1 more source

Effects of mass concentration and curing age on the mechanical properties and damage evolution of aeolian sand backfill

Scientific Reports
As the critical load-bearing structure in the management of open-pit mine goaf areas, the mechanical properties of cemented backfill material play a decisive role in strata stability. This study investigates the influence of solids mass concentration (a)
Guibin Zhao, Yafei Zhang, Guangli Zhang, Hao Zhang, Xiufeng Zhang   +4 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Optimum ramp design in open pit mines

Computers & Operations Research, 2020
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Juan L. Yarmuch, Marcus Brazil, J. Hyam Rubinstein, Doreen A. Thomas   +3 more
openaire   +2 more sources

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Key Technology and Intelligent Management and Control Concept of Intelligent Construction of Open-pit Coal Mine

Meikuang Anquan, 2020
This paper first analyzes the existing problems of open-pit coal mine from the perspective of industry background, policy guidance, management and control concept, expounds the necessity of establishing intelligent mine, studies the definition, overall ...
HE Shuai, WANG Haiyang, ZHAO Li
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source