Results 91 to 100 of about 16,453,163 (304)
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Support mechanisms provided by FLOSS foundations and other entities
Foundations function as a vital institutional support infrastructure for many of the most successful open-source projects, but the different roles played by these support entities are understudied in Free/Libre and Open Source Software (FLOSS) research ...
Juho Lindman, Imed Hammouda
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Selection and Management of Open Source Software in Libraries
Open source software was a revolutionary concept among computer programmers and users. To a certain extent open source solutions could provide an alternative solution to costly commercial software.
Vimal Kumar, V.
core
Ivermectin is a common macrocyclic lactone that is proven to be active against a wide range of parasites in veterinary medicine. This article presents a narrative review that combines evidence on the antiparasitic effects of ivermectin, its therapeutic ...
Matthew T. J. Halma +6 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Usability discussions in open source development
The public nature of discussion in open source projects provides a valuable resource for understanding the mechanisms of open source software development. In this paper we explore how open source projects address issues of usability.
Nichols, David M., Twidale, Michael B.
core
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
The LaTeX project: A case study of open-source software [PDF]
This is a case study of TeX, a typesetting software that was developed by Donald E. Knuth in the late 70's. Released with an open source license, it has become a reference in scientific publishing. TeX is now used to typeset and publish much of the world'
Alexandre Gaudeul
core +2 more sources

