Results 101 to 110 of about 2,806,784 (213)

Open-Source Multinuclear Low-Field Preclinical MRI Scanner. [PDF]

NMR Biomed
Rodriguez GG, Korchak S, von Petersdorff-Campen C, Sucre O, Felger J, Mei R, Glöggler S.   +6 more
europepmc   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Editorial: Alleviating age-related disease burden

Frontiers in Aging
Matthew Halma, Sidra Hassaan, Jack A. Tuszynski, Jack A. Tuszynski   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Machine Learning Approaches Identify Chemical Features for Stage-Specific Antimalarial Compounds

ACS Omega, 2023
Ashleigh van Heerden, Gemma Turon, Miquel Duran-Frigola, Nelishia Pillay, Lyn-Marié Birkholtz   +4 more
doaj   +1 more source

Open-Source Benchmarking of Plant-Based and Animal Meats. [PDF]

Foods
van den Bedem SD, Kuhl E, Cotto C.
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Steering open-source AI to accelerate the sustainable development goals. [PDF]

Nat Commun
Chen M, Wu K, Pradhan P, Allen C, Nativi S, Hubacek K, Voinov A, Creutzig F, Filatova T, Boers N, Meadows M, Ma P, Biermann F, Schellnhuber HJ, Ludden J, Paradiso M, Batty M, Guo H, Cao M, Hou P, Lü G.   +20 more
europepmc   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

IndentAtlas: an open-source toolbox for indentation mapping analysis. [PDF]

MethodsX
Vellwock AE, Amini S, Micheletti C.
europepmc   +1 more source