Results 101 to 110 of about 378,967 (294)
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Perinatal maternal and neonatal behaviour in\ud the captive reticulated giraffe [PDF]
A captive reticulated giraffe was observed constantly for three weeks prior to, and periodically for 90 days subsequent to, the birth of her calf. Extensive observations were made of the birth sequence, feeding, drinking, sleeping and one instance of an ...
Kristal, Dr. Mark B., Noonan, Michael
core
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Struma Ovarii Associated with Pseudo- Meigs’Syndrome [PDF]
Struma ovarii is a specialized ovarian teratoma composed predominantly of mature thyroid tissue. It is associated with pleural effusion and ascites (Pseudo-Meigs’ syndrome) in 5% of cases.
Gangane, NM, Gulhane, SR, Sinha, RT
core +1 more source
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Getting Better in Open Abdomen Surgery
Şahin Kahramanca, Turgut Anuk
doaj +1 more source
Descriptions of new species of the New World genus Perilypus Spinola (Coleoptera: Cleridae: Clerinae) [PDF]
Thirty-two new species of Perilypus Spinola (Coleoptera: Cleridae: Clerinae) are described; they are Perilypus ancorus, P. angustatus, P. aquilus, P. arenaceus, P. caligneus, P. cartagoensis, P. collatus, P. comosus, P. concisus, P.
Opitz, Weston
core
Automated Lymph Node (LN) detection is an important clinical diagnostic task but very challenging due to the low contrast of surrounding structures in Computed Tomography (CT) and to their varying sizes, poses, shapes and sparsely distributed locations ...
Cherry, Kevin M. +8 more
core +1 more source
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source

