Results 201 to 210 of about 2,539,381 (235)
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia +9 more
wiley +1 more source
Open Access Publishing: First Among Equals
Medical Journal of Dr. D.Y. Patil VidyapeethAmitav Banerjee
doaj +1 more source
Some of the next articles are maybe not open access.
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The Downside of Open-Access Publishing
New England Journal of Medicine, 2013The open-access model in which authors pay to have their work published offers an alternative way of financing quality control in scholarly publishing. But it also opens up opportunities for unscrupulous online “vanity presses” to exploit authors for profit.
Charlotte Haug
exaly +3 more sources
Electronic Scholarly Publishing and Open Access
Journal of Information Science, 2008A review of recent developments in electronic publishing, with a focus on Open Access (OA) is provided. It describes the two main types of OA, i.e. the `gold' OA journal route and the `green' repository route, highlighting the advantages and disadvantages of the two, and the reactions of the publishing industry to these developments.
Charles Oppenheim
exaly +3 more sources
The Oligopoly of Open Access Publishing
Scientometrics, 2023Open access (OA) publishing is often viewed as a promising solution for the future of scholarly publishing, as it has the potential to reduce global inequalities in access to scientific literature by removing paywalls. However, the adoption of OA publishing may not necessarily lead to a decrease in the overall cost of knowledge dissemination, as ...
Fei Shu, Vincent Larivière
openaire +1 more source
Open access publishing in science
Communications of the ACM, 2009While the evolving information society is freely opening and sharing its diaries, social networks and source codes, it remains to be seen if the same will come true for scientific knowledge. Despite strong sympathy for the idea, scientists balk at Open Access publishing. Here we shed some light on why this is so.
Florian Mann +3 more
openaire +1 more source