Results 111 to 120 of about 626,537 (285)

Contextualizing Openness: Situating Open Science [PDF]

, 2019
Contextualizing Openness offers a fascinating look at Open Science and the democratization of knowledge in international development and social transformation with a focus on the Global South.
Albornoz, Denisse, Okune, Angela, Chan, Leslie, Posada,Alejandro, Hillyer, Rebecca   +4 more
core   +1 more source

Offene Metadaten und datenanalytische Forschungsservices in der Open-Access-Transformation

Bibliothek
The open access transition aims to replace traditional subscription models with Open Access (OA) models. Transformative agreements between academic institutions, consortia, and publishers play a central role in this process.
Dörner Sophia
doaj   +1 more source

Open-Access-Transformation - Die Ablösung des Subskriptionswesens durch Open-Access-Geschäftsmodelle

, 2017
Hinter dem Thema Open Access steht eine Bewegung, die in den letzten Jahren sehrviel erreichen konnte. Beeindruckend ist, an wie vielen wissenschaftlichen Einrichtungenentsprechende Policies und Mandate verabschiedet wurden, wo überall institutionelleRepositorien als Instrumente des „Grünen Weges“ eingerichtet wurdenund über welche Vielfalt an ...
Schimmer, Ralf, Geschuhn, Kai
openaire   +2 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

The digital transformation of the information professions: Exploring the impact of digital publishing and open access

Information Research: An International Electronic Journal
Introduction. The information professions encompass a range of interconnected disciplines that contribute to the effective creation, processing, management, dissemination, and preservation of information and knowledge in diverse formats and contexts ...
Suliman Hawamdeh, Daniel Alemeneh, Jeff Allen   +2 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Open freedoms : open practices [PDF]

, 2013
Contemporary open education practices are based on free software and free culture movements. Join Paul Stacey from Creative Commons as he explores the extent to which Open Educational Resources, MOOC’s, open access, and other open education innovations ...
Stacey, Paul
core  

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

DeepGreen – Open Access Transformation in Practice

, 2019
Since 2011 so-called Alliance licenses funded by the German Research Foundation (DFG) include an open access component which allows authors to make their articles, after a shortened embargo period, publicly available through their institutional or subject-based repositories. If the institution negotiated the license, she acts as a representative of the
Boltze, Julia, Wannick, Eike
openaire   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source