Results 91 to 100 of about 626,537 (285)

Trans-O-MIM-An International Research Project on Open Access Transformation: Outcomes and Lessons Learned. [PDF]

open access: yesMethods Inf Med, 2023
Haux R   +5 more
europepmc   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Open-Access-Monitoring zwischen Wunsch und Wirklichkeit [PDF]

open access: yes, 2017
Open-Access-Monitoring ist ein vage definiertes, aber immer wichtiger werdendes Tätigkeitsfeld im Open-Access-Kontext. Es korrespondiert mit Open-Access-Strategien und -Vorgaben und dient sowohl der Planung von Open-Access-Aktivitäten als auch der ...
Tullney, Marco (5276728), Tullney, Marco
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Open transformation of academic publishing: a review of open access developments in the west in 2014 [PDF]

open access: yes, 2015
This invited review looks at OA developments in the US and EU from three perspectives: OA policies, 'gold' OA, and 'green OA'. The OA mandates have become a global trend, but the practical transformation of academic publishing remains uncertain.
Ren, Xiang
core  

Monitoring, Informationsbudget & Alma

open access: yeso-bib. Das offene Bibliotheksjournal, 2023
Nina Schönfelder
doaj   +1 more source

Open Access an der Medizinischen Universität Wien: Status und Perspektiven aus dem Blickwinkel der Bibliothek

open access: yesGMS Medizin – Bibliothek – Information, 2019
The Medical University Vienna is one of the universities with the highest publication-output in Austria. A considerable proportion of these publications already fall into the area of open access, not least through the initiatives of the Austrian ...
Bauer, Bruno   +2 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Vom Informationsversorger zum Forschungsdienstleister – Änderung der Wahrnehmung bibliothekarischer Arbeit durch Open Access an der Bibliothek Medizin/Naturwissenschaften der Universität Leipzig

open access: yesGMS Medizin – Bibliothek – Information, 2019
This practice report reflects on the relevance of the Leipzig University Library’s various offerings and services in the field of open access publishing as well as current and future points of contact and challenges related to the open access ...
Vieler, Astrid, Wöckel, Claudia
doaj   +1 more source

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