Results 71 to 80 of about 626,537 (285)
From the DEAL engine room — an interview with Bernhard Mittermaier
For more than a year there is one topic that has kept the German research community in suspense: the DEAL with the three dominating scholarly publishers Elsevier, Springer Nature and Wiley. The hoped-for deal is a Germany-wide contract, which in addition
Bernhard Mittermaier
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
OAPEN-NL: a project exploring open access monograph publishing in the Netherlands [PDF]
Executive summary: Monographs still play an important role in scholarly communication, particularly in the Humanities and Social Sciences. The availability of publication outlets for research monographs is crucial to the careers of researchers and to ...
core
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Austrian Transition to Open Access (AT2OA) [PDF]
In 2016 the expert group called “Open Access Network Austria” (OANA) published 16 recommendations on how Austria should support a transition to open access (OA).
Patrick Danowski +3 more
core +1 more source
Ralf Schimmer beantwortet Fragen über die Positionierung der Max Planck Gesellschaft zu Open Access und spricht auch über Motive und Zeitpunkt der Veröffentlichung der programmatischen Schrift „Disrupting the subscription journals' business model for the
Ralf Schimmer, Bruno Bauer
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Mit der Etablierung von Open Access als Standardmodell des wissenschaftlichen Publizierens verlagert sich der Fokus von Subskriptions- auf Publikationskosten. Die zuverlässige und vollständige Erfassung dieser Kosten stellt eine große Herausforderung für
Claudia Frick, Christian Kaier
doaj +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source

