Results 81 to 90 of about 742,533 (245)
Open-Access-Transformation - Die Ablösung des Subskriptionswesens durch Open-Access-Geschäftsmodelle
Hinter dem Thema Open Access steht eine Bewegung, die in den letzten Jahren sehrviel erreichen konnte. Beeindruckend ist, an wie vielen wissenschaftlichen Einrichtungenentsprechende Policies und Mandate verabschiedet wurden, wo überall institutionelleRepositorien als Instrumente des „Grünen Weges“ eingerichtet wurdenund über welche Vielfalt an ...
Schimmer, Ralf, Geschuhn, Kai
openaire +2 more sources
Early‐Phase Research in Pediatric Neuro‐Oncology
Pediatric Blood &Cancer, EarlyView.
Jonathan Cunningham
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Introduction. The information professions encompass a range of interconnected disciplines that contribute to the effective creation, processing, management, dissemination, and preservation of information and knowledge in diverse formats and contexts ...
Suliman Hawamdeh +2 more
doaj +1 more source
DeepGreen – Open Access Transformation in Practice
Since 2011 so-called Alliance licenses funded by the German Research Foundation (DFG) include an open access component which allows authors to make their articles, after a shortened embargo period, publicly available through their institutional or subject-based repositories. If the institution negotiated the license, she acts as a representative of the
Boltze, Julia, Wannick, Eike
openaire +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Offene Metadaten und datenanalytische Forschungsservices in der Open-Access-Transformation
The open access transition aims to replace traditional subscription models with Open Access (OA) models. Transformative agreements between academic institutions, consortia, and publishers play a central role in this process.
Dörner Sophia
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Strategic Aspects of the Open Access Transformation
Präsentation für den Online-Workshop "Finanzierungsströme für die Open-Access-Transformation – Überblick und Stand der Diskussion" am 13.09.2023, veranstaltet vom BMBF-Projekt open-access ...
openaire +1 more source

