Results 101 to 110 of about 96,836 (298)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Role Of Green Open Space In Performance Improvement Of Malang City Center

Journal of Innovation and Applied Technology, 2018
This study is a continuation of previous research [5],[6],[7], on the hierarchy of the Green Open Space’s role of the city based on its 9 classifications (Green Line, City Park, Urban forest, Garden Tomb, Sports Park, Rotonde, Monument Park, Playground ...
subhan ramdlani, Lisa Dwi Wulandari
doaj   +1 more source

Analysis of Green Open Space Policy in Urban

PUBLIC POLICY (Jurnal Aplikasi Kebijakan Publik & Bisnis)
This research aims to analyze the implementation of Regional Regulation Policy Number 1 of 2020 concerning Regional Spatial Planning in the development of Green Open Space in Probolinggo City. This investigation utilizes qualitative research methodology, employing a case study approach. Data gathering involves observation, interviews, and documentation
Diah Putri Hasanah, Lukman Arif
openaire   +1 more source

Use pattern analysis in green open spaces of Malaysia [PDF]

, 2013
Housing development in Malaysia is bounded to obey several acts and legislation which among them is the Planning Guidelines and Standards set out by the Town and Country Planning Department of Malaysia. This guideline serves as a written statement that
Abdul Malek, Nurhayati
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

From green open space to green infrastructure: The potential of green open space optimization towards sustainable cities in Bekasi City & Regency, Indonesia

IOP Conference Series: Earth and Environmental Science, 2019
Abstract Urban growth dynamics have resulted an increase in population and rapid conversion of green open space (GOS) into built-up areas. Despite the minimum standard provision has been stated 30% on spatial regulation Law No 26/2007, Bekasi City Government has been struggling to preserve their remaining valuable green open spaces. This
H Ajrina, I Kustiwan
openaire   +1 more source

Value of urban green spaces in promoting healthy living and wellbeing: prospects for planning

, 2015
Andrew Chee Keng Lee,1 Hannah C Jordan,1 Jason Horsley2 1Section of Public Health, School of Health and Related Research, University of Sheffield, 2Sheffield City Council, Sheffield, UK Abstract: There has been considerable work done in recent years ...
Lee ACK, Horsley J, Jordan HC
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Green open space planning based on spatial justice in Jakarta: Study of child friendly integrated public spaces/RPTRA and general green open space

Background: Urbanization has significantly reduced green open spaces in Jakarta, impacting ecological balance and quality of life. While the importance of green open spaces for urban quality of life is well understood, comprehensive studies on spatial ...
Saputra, Erlangga, Ramadhan, Aswin Kurnia   +1 more
core   +3 more sources