An RNA Sequencing Analysis of Glaucoma Genesis in Mice [PDF]
arXiv, 2022 Glaucoma is the leading cause of irreversible blindness in people over the age of 60, accounting for 6.6 to 8% of all blindness in 2010, but there is still much to be learned about the genetic origins of the eye disease. With the modern development of Next-Generation Sequencing (NGS) technologies, scientists are starting to learn more about the genetic
arxiv
Reductions in retrobulbar and retinal capillary blood flow strongly correlate with changes in optic nerve head and retinal morphology over four years in open-angle glaucoma patients of African descent compared to patients of European descent [PDF]
, 2016 Purpose To investigate the relationship of changes in ocular blood flow with optic nerve head and retinal morphology in open-angle glaucoma patients of African versus European descent over four years.
Carr, Joseph +9 more
core +1 more source
VIEW, EarlyView.Fire‐related smoke inhalation‐induced acute lung injury (SI‐ALI) poses a significant public health risk, yet effective treatments are limited due to the lack of suitable models. This study developed a more realistic model of SI‐ALI using organ‐on‐a‐chip and organoid technologies, identified key molecules such as catechol‐O‐methyltransferase and ...
Junmin Li +12 more
wiley +1 more source
A study of primary open angle glaucoma in Diabetic patients [PDF]
Perspectives In Medical Research, 2018 Introduction: Primary open angle glaucoma is the commonest form of glaucoma accounting for atleast half of all the glaucomas. Intra Ocular Pressure is a definite and important risk factor for developing glaucomatous damage. Open-angle glaucoma is an
Shri Krishna Ingle1 , Yasam Soumya2 , Jaganmohan Rao3 , S. Kapil4
doaj
A Randomised Open Label Comparative Clinical Trial on the Efficacy of Latanoprost and Timolol in Primary Open Angle Glaucoma [PDF]
Journal of Clinical and Diagnostic Research, 2016 Introduction: Timolol, a beta blocker, is the most commonly prescribed first line therapy in the treatment of primary open angle glaucoma. Latanoprost, a prostaglandin analogue, is a novel drug in glaucoma therapy.
Sharadashri Rao, P.V. Narayanan
doaj +1 more source
GAMMA Challenge:Glaucoma grAding from Multi-Modality imAges [PDF]
arXiv, 2022 Color fundus photography and Optical Coherence Tomography (OCT) are the two most cost-effective tools for glaucoma screening. Both two modalities of images have prominent biomarkers to indicate glaucoma suspected. Clinically, it is often recommended to take both of the screenings for a more accurate and reliable diagnosis.
arxiv
DNA sequence variants in the LOXL1 gene are associated with pseudoexfoliation glaucoma in a U.S. clinic-based population with broad ethnic diversity [PDF]
, 2008 Background Pseudoexfoliation syndrome is a major risk factor for glaucoma in many populations throughout the world. Using a U.S. clinic-based case control sample with broad ethnic diversity, we show that three common SNPs in LOXL1 previously associated ...
B Nemesure +48 more
core +3 more sources
Macromolecular crystallography at Elettra: current and future perspectives
Journal of Synchrotron Radiation, EarlyView.The XRD2 beamline at Elettra‐Sincrotrone Trieste has been in operation since 2018 and is dedicated to macromolecular crystallography for both academic and industrial research, a role partially fulfilled, before 2018, by XRD1, a general‐purpose diffraction beamline.
Raghurama P. Hegde +13 more
wiley +1 more source
Homocysteine and risk of open-angle glaucoma
Journal of Neural Transmission, 2002 Homocysteine levels and the frequency of heterozygous methylenetetrahydrofolate reductase (MTHFR) C677T mutation are increased in open-angle glaucoma. Since homocysteine can induce vascular injury, alterations in extracellular matrix remodelling, and neuronal cell death, these findings may have important implications for understanding glaucomatous ...
Bleich, S +7 more
openaire +4 more sources
Circulating Platelet Aggregates and Progression of Visual Field Loss in Glaucoma [PDF]
, 2002 The aim of the study was to assess a relationship between circulating platelet aggregates (CPA) and progression of visual field loss in primary open-angle glaucoma patients.
D. Buković +4 more
core +1 more source