Results 111 to 120 of about 163,643 (341)

Single oral administration of dronabinol increases ocular blood flow in patients with glaucoma

Acta Ophthalmologica, EarlyView.
Abstract Purpose Glaucoma is a leading cause of irreversible blindness globally, primarily driven by elevated intraocular pressure (IOP). Still, some patients progress despite significant IOP lowering, potentially due to impaired ocular blood flow. This study aimed to evaluate the effects of dronabinol, a synthetic tetrahydrocannabinol derivative, on ...
Theresa Lindner, Viktoria Pai, Patrick Janku, Nikolaus Hommer, Anton Hommer, Marihan Abensperg‐Traun, Liudmyla Petric, Leopold Schmetterer, Gerhard Garhöfer, Doreen Schmidl   +9 more
wiley   +1 more source

A large multi-ethnic genome-wide association study identifies novel genetic loci for intraocular pressure. [PDF]

, 2017
Elevated intraocular pressure (IOP) is a major risk factor for glaucoma, a leading cause of blindness. IOP heritability has been estimated to up to 67%, and to date only 11 IOP loci have been reported, accounting for 1.5% of IOP variability.
Banda, Yambazi, Choquet, Hélène, Hoffmann, Thomas J, Jorgenson, Eric, Kvale, Mark N, Melles, Ronald, Nair, K Saidas, Risch, Neil, Schaefer, Catherine, Thai, Khanh K, Yin, Jie   +10 more
core   +3 more sources

Choroidal vascular index in patients with open angle glaucoma and preperimetric glaucoma

PLoS ONE, 2019
Purpose To evaluate choroidal structural changes in glaucoma using choroidal vascularity index (CVI) compared to healthy subjects. Methods This retrospective study included 56 patients with open angle glaucoma (OAG), 50 patients with preperimetric ...
Yuli Park, K. Cho
semanticscholar   +1 more source

Clinical outcomes of the PAUL glaucoma implant in primary open‐angle and pseudoexfoliative glaucoma eyes after failed glaucoma surgeries

Acta Ophthalmologica, EarlyView.
Abstract Purpose This study assesses the PAUL® glaucoma implant (PGI) in primary open angle glaucoma (POAG) and pseudoexfoliative glaucoma (PEXG) after failed glaucoma surgery. Given PEXG's more aggressive nature, limited research exists on PGI outcomes in this subgroup. This study aims to compare PGI's efficacy and safety in both conditions. Methods A
Constance Liegl, Leonie Bourauel, Benjamin Aretz, Diana Samarghitan, Wolfgang Walz, Michael Petrak, Frank G. Holz, Raffael Liegl, Karl Mercieca   +8 more
wiley   +1 more source

Rates of macular volume changes in different stages and courses of primary open-angle glaucoma

Journal of Ophthalmology
Purpose: To examine macular volume changes as assessed by optical coherence tomography (OCT) and rates of these changes in different stages and courses of primary open-angle glaucoma (POAG).
M. V. Panchenko, O. M. Honchar, H. Yu. Panchenko, I. V. Kitchenko   +3 more
doaj   +1 more source

Assessment of polygenic effects links primary open-angle glaucoma and age-related macular degeneration

Scientific Reports, 2016
Primary open-angle glaucoma (POAG) and age-related macular degeneration (AMD) are leading causes of irreversible blindness. Several loci have been mapped using genome-wide association studies.
G. Cuéllar-Partida, J. Craig, K. Burdon, Jie-Jin Wang, B. Vote, E. Souzeau, I. McAllister, T. Isaacs, Stewart R. Lake, D. Mackey, I. Constable, P. Mitchell, A. Hewitt, S. Macgregor   +13 more
semanticscholar   +1 more source

Threat to fixation and vision‐related quality of life in patients with open‐angle glaucoma

Acta Ophthalmologica, EarlyView.
Abstract Purpose We aimed to investigate the association between overlapping threat to fixation (TTF) and vision‐related quality of life (VRQoL) in patients with manifest open‐angle glaucoma (OAG). Methods Overall, 316 patients with manifest OAG were recruited from the glaucoma outpatient department of Skåne University Hospital, Malmö, Sweden, between ...
Charlotte Almer, Dorothea Peters
wiley   +1 more source

Epidemiological characterization of primary open-angle glaucoma

Medisur, 2010
Background: The primary open-angle glaucoma is a problem for public health all over the world. It is a silent and slowly progressive disease leading to blindness.
Leonor Rosario Díaz Alfonso, Bárbara Nuria Suárez Rodríguez, Mariela Julia Curbelo, Yusdenia Soto Serrano, Armando Rafael Milanés Armengol   +4 more
doaj   +2 more sources

The role of the local and general somatic factors for the open-angle glaucoma development in patients with eye manifestations of pseudoexfoliation syndrome

Офтальмохирургия, 2013
Pseudoexfoliation syndrome (PEX) is one of the best known triggers of glaucoma. The development of the open-angle glaucoma only in some patients with the PEX with definite local and general risk factors requires a further research. Purpose.
V.V. Agafonova,, M.Z. Frankovska-Gerlak, T.V. Sokolovskaya, P.E. Brizhak,, A.N. Bessarabov   +4 more
doaj  

Managing primary open-angle glaucoma in the setting of suboptimal surgical outcomes in the fellow eye [PDF]

, 2023
Marshall J. Huang, Thomas W. Samuelson, Ticiana De Francesco, Ariana M. Levin, Erin G. Sieck, Gus Gazzard, Matt Porter, Mark Gallardo, Robert Chang, Wendy W. Liu, Craig J. Chaya, Shawn Gulati, Manjool Shah   +12 more
openalex   +1 more source