Results 31 to 40 of about 39,992 (254)

Novel therapies for open-angle glaucoma [PDF]

F1000Prime Reports, 2014
Open-angle glaucoma is a multifactorial optic neuropathy characterized by progressive loss of retinal ganglion cells and their axons. It is an irreversible disease with no established cure. The only currently approved treatment is aimed at lowering intraocular pressure, the most significant risk factor known to date. However, it is now clear that there
Jenny Wang, Annahita Amireskandari, Scott Wentz, Brent Siesky, Nathaniel Kim, Alon Harris   +5 more
openaire   +3 more sources

Broad‐Spectrum Diffusion Coefficient Measurements via Surface Plasmon Resonance: From Thermodynamics to Protein Conformational Disorders

ChemPhysChem, EarlyView.
Recent advancements in surface plasmon resonance protocols and simulations have enhanced the measurement and prediction of diffusion coefficients (D) for chemical species in microfluidic channels. These developments enable precise determination of D values for molecules ranging from a few angstroms to nanometric aggregates, facilitating detailed ...
Giuseppe Stefano Basile, Damiano Calcagno, Nunzio Tuccitto, Diego Sbardella, Giuseppe Grasso   +4 more
wiley   +1 more source

Mechanisms in open-angle glaucoma. [PDF]

British Journal of Ophthalmology, 1978
One hundred and nineteen eyes from 68 patients with open-angle glaucoma were provoked by means of a pilocarpine phenylephrine provocative test. In 22% the response was the same as that seen in normal eyes. In 78% the response was the same as that seen in contralateral eyes at risk to the development of closed-angle glaucoma, which do not develop a ...
openaire   +2 more sources

Fluorescence Lifetime Imaging Techniques—A Review on Principles, Applications and Clinical Relevance

Journal of Biophotonics, EarlyView.
This article gives an overview of the most frequently used fluorescence‐lifetime imaging (FLIM) techniques, their capabilities and typical applications in biology and clinical studies. ABSTRACT This article gives an overview of the most frequently used fluorescence‐lifetime imaging (FLIM) techniques, their capabilities, and typical applications ...
V. I. Shcheslavskiy, M. V. Shirmanova, K. S. Yashin, A. C. Rück, M. C. Skala, W. Becker   +5 more
wiley   +1 more source

Cognition–Eye–Brain Connection in Alzheimer's Disease Spectrum Revealed by Multimodal Imaging

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background The connection between cognition, eye, and brain remains inconclusive in Alzheimer's disease (AD) spectrum disorders. Purpose To explore the relationship between cognitive function, retinal biometrics, and brain alterations in the AD spectrum. Study Type Prospective.
Yan Shi, Tingting Shen, Su Yan, Jianwen Liang, Tianyunxi Wei, Yijin Huang, Rong Gao, Ning Zheng, Renpuchi Ci, Min Zhang, Xiaoying Tang, Yuanyuan Qin, Wenzhen Zhu   +12 more
wiley   +1 more source

Difference of Heat Shock Protein 70 Serum Level Between Primary Angle Closure Glaucoma and Open Angle Glaucoma Patients: Indonesia Single Center Experience

Folia Medica Indonesiana, 2021
This study aimed to analyze the differences in Hsp 70 serum levels in patients with primary angle-closure compared to patients with open-angle glaucoma at Dr. Soetomo General Academic Hospital, Surabaya, East Java.
Mohamad Nurdin Zuhri, Nurwasis Nurwasis, Endang Retnowati, Windhu Purnomo   +3 more
doaj   +1 more source

Preclinical Testing of 3D Printed, Cell Loaded Hydrogel Based Corneal Substitutes on Rabbit Model

Macromolecular Bioscience, EarlyView.
This study reports on 3D‐printed methacrylated gelatin (GelMA) implants designed to serve as corneal stroma substitutes. The implants are characterized for their transparency, mechanical strength, and cytocompatibility. In vivo tests on rabbits demonstrate successful integration, with histopathological analysis showing tissue regeneration, appropriate ...
Deniz Basoz, Aslihan Akalinli, Senem Buyuksungur, A. R. Cenk Celebi, Deniz Yucel, Nesrin Hasirci, Vasif Hasirci   +6 more
wiley   +1 more source

Selection of Medical Therapy in Glaucoma Patients in the Outpatient Eye Clinic Soetomo General Academic Hospital Surabaya

Folia Medica Indonesiana, 2021
Highlight: • Medical therapy selection in the outpatient eye clinic were determined. • Treatment of prostaglandin analogue therapyfor primary open angle glaucoma was the most common glaucoma type.
Venansya Maulina Praba, Yulia Primitasari, Mohammad Fathul Qorib, Rozalina Loebis   +3 more
doaj   +1 more source

Risk of open angle glaucoma due to tumor necrosis factor alpha gene polymorphisms

Electronic Physician, 2016
Introduction: Axonal degeneration and retinal ganglion cell apoptosis in glaucoma is associated with tumor necrosis factor alpha (TNF-α), which is an important pro-inflammatory cytokine.
Mona Abdel Hamid, Leqaa Moemen, Hany Labib, Hazem Helmy, Tarek Elsergany   +4 more
doaj   +1 more source

Secretome Profiling in Axon Regeneration: Emerging Techniques and Therapeutic Translation

Sensory Neuroscience, EarlyView.
ABSTRACT The secretome refers to the in vivo ensemble of molecular entities that are found in interstitial spaces. It is then the mere secreted products of the cells, as all biomolecules in the interstitial cellular spaces also undergo modifications. The fractionated secretome may hold potential as a cell‐free therapy option due to its role in tissue ...
Maria D. Cabrera, Nicole Ramones, Isabella Moceri, Sanjoy K. Bhattacharya   +3 more
wiley   +1 more source