Results 71 to 80 of about 266,911 (306)
Large-scale machine learning-based phenotyping significantly improves genomic discovery for optic nerve head morphology [PDF]
arXiv, 2020 Genome-wide association studies (GWAS) require accurate cohort phenotyping, but expert labeling can be costly, time-intensive, and variable. Here we develop a machine learning (ML) model to predict glaucomatous optic nerve head features from color fundus photographs. We used the model to predict vertical cup-to-disc ratio (VCDR), a diagnostic parameter
arxiv
Mechanisms in open-angle glaucoma. [PDF]
British Journal of Ophthalmology, 1978 One hundred and nineteen eyes from 68 patients with open-angle glaucoma were provoked by means of a pilocarpine phenylephrine provocative test. In 22% the response was the same as that seen in normal eyes. In 78% the response was the same as that seen in contralateral eyes at risk to the development of closed-angle glaucoma, which do not develop a ...
openaire +2 more sources
Folia Medica Indonesiana, 2021 Highlight: • Medical therapy selection in the outpatient eye clinic were determined. • Treatment of prostaglandin analogue therapyfor primary open angle glaucoma was the most common glaucoma type.
Venansya Maulina Praba +3 more
doaj +1 more source
Advanced Microfluidic‐Based Wearable Electrochemical Sensors for Continuous Biochemical Monitoring
Advanced Electronic Materials, EarlyView.Microfluidic‐based wearable electrochemical sensors are transforming non‐invasive health monitoring through real‐time biochemical analysis of sweat, saliva, and interstitial fluid. This review explores advances in microfluidic design, fabrication, and sensor integration while addressing biofluid variability, material compatibility, and scalability.
Sehyun Park +5 more
wiley +1 more source
Early Primary Open-Angle Glaucoma [PDF]
, 2018 Glaucoma is the leading cause of irreversible blindness worldwide and is projected to affect more than 79.6 million people by 2020, over 10% of whom will be bilaterally blind.1 This multifactorial progressive optic neuropathy causes characteristic ...
Lifferth, Austin R.
core +2 more sources
Costello Syndrome and Ophthalmologic Issues: Unveiling the Unseen
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Costello syndrome (CS) is an ultra‐rare condition belonging to the RASopathies, a group of disorders characterized by aberrant RAS/MAPK pathway signaling, which is involved in ocular development and in some eye pathologies. However, only a few studies assessing the ophthalmic features of individuals with CS are available.
Sofia Peschiaroli +13 more
wiley +1 more source
Reconstruction and Quantification of 3D Iris Surface for Angle-Closure Glaucoma Detection in Anterior Segment OCT [PDF]
arXiv, 2020 Precise characterization and analysis of iris shape from Anterior Segment OCT (AS-OCT) are of great importance in facilitating diagnosis of angle-closure-related diseases. Existing methods focus solely on analyzing structural properties identified from the 2D slice, while accurate characterization of morphological changes of iris shape in 3D AS-OCT may
arxiv
The genetics of primary open angle glaucoma [PDF]
British Journal of Ophthalmology, 1997 The advent of the discipline of molecular genetics over the past decade has led to a dramatic growth in our understanding of the genetics of a myriad of diseases. Ophthalmology has benefited greatly from this new technology, with significant advances in our knowledge about conditions as varied as aniridia and retinitis pigmentosa.1 2 Our understanding ...
Amanda J. Churchill +4 more
openaire +3 more sources
Risk of open angle glaucoma due to tumor necrosis factor alpha gene polymorphisms
Electronic Physician, 2016 Introduction: Axonal degeneration and retinal ganglion cell apoptosis in glaucoma is associated with tumor necrosis factor alpha (TNF-α), which is an important pro-inflammatory cytokine.
Mona Abdel Hamid +4 more
doaj +1 more source
Pseudoexfoliative Syndrome and Pseudoexfoliative Glaucoma in Primorsko-Goranska County [PDF]
, 2010 The aim of this study is to evaluate pseudoexfoliative glaucoma (PEX) in Primorsko-Goranska County, Croatia, and its characteristics comparing to primary open angle glaucoma (POAG).
Damir Kovačević +3 more
core +1 more source