ABSTRACT Diabetic wounds are characterized by persistent inflammation and impaired immune resolution, yet the therapeutic translation of single‐cell atlases into rational immunomodulatory strategies remains limited. Here, integration of diabetic‐wound single‐cell transcriptomic datasets identifies a neutrophil subpopulation enriched in cluster of ...
Tairong Cui +12 more
wiley +1 more source
India's digital-first approach to sickle cell disease elimination. [PDF]
Nair AR.
europepmc +1 more source
SCHOLARLY COMMUNICATIONS: The open archives initiative
openaire +2 more sources
Acinar‐Derived Organoids Reveal Stage‐Specific Control of Acinar Plasticity
An acinar‐derived organoid system maintains adult pancreatic acinar identity ex vivo, converts it along an ordered acinar‐to‐ductal‐like trajectory, and then partially restores it. Each transition carries its own signal requirement, with EGF/EGFR initiating conversion and a staged glucocorticoid–IGF1R switch driving redifferentiation.
Yongfei Hou +10 more
wiley +1 more source
Young Investigator Award 2026: Extent and incidence of pseudo-worsening of kidney function due to oral antitumor therapeutics in the AMBORA cohort: an analysis of real-world data. [PDF]
Sponfeldner MI.
europepmc +1 more source
The Open Archives Initiative: application and exploitation
openaire +2 more sources
A robust periosteal organoid system enables long‐term expansion while preserving native cellular heterogeneity. These organoids recapitulate functional niche environments, support hematopoietic stem cell maintenance, and attenuate aging‐associated decline ex vivo.
Jia Qing +9 more
wiley +1 more source
A Reexamination of Dr. Masanao Goto's Leprosy Treatment in Hawai'i: New Insights from Japanese and Hawaiian Sources. [PDF]
Yuji K, Yuji W.
europepmc +1 more source
In Vivo CRISPR Screen Identifies RPS19 as an Immunotherapy Target in Hepatocellular Carcinoma
By employing in vivo CRISPR functional screening, we identify ribosomal protein RPS19 as a pivotal mediator driving immune evasion in hepatocellular carcinoma, wherein tumor‑released RPS19 binds C5aR1 on tumor‑associated macrophages to initiate downstream immunosuppressive signaling; SP94‑peptide‑modified SNPSS nanoparticles deliver Cas9/sgRPS19 ...
Lei He +20 more
wiley +1 more source
Arts as a resource in global mental health: a mixed-methods exploratory study of therapeutic arts, photography and cultural archiving with formerly captured Yazidi women. [PDF]
Sajnani N +7 more
europepmc +1 more source

