Results 121 to 130 of about 841,164 (237)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Bed sill effectiveness in reducing flow separation at open channel confluences: an openfoam-VOF 3D CFD study. [PDF]

Sci Rep
Sandilya SS, Das BS, Pandey AK.
europepmc   +1 more source

Open channel block of Kv1.4 potassium channels by aripiprazole. [PDF]

Korean J Physiol Pharmacol, 2020
Park J, Cho KH, Lee HJ, Choi JS, Rhie DJ.   +4 more
europepmc   +1 more source

Direct Scaling of Measure on Vortex Shedding through a Flapping Flag Device in the Open Channel around a Cylinder at Re∼10³: Taylor's Law Approach. [PDF]

Sensors (Basel), 2021
De Bartolo S, Vittorio M, Francone A, Guido F, Leone E, Mastronardi VM, Notaro A, Tomasicchio GR.   +7 more
europepmc   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Impact of bed roughness configurations on flow dynamics and hydraulic resistance in open-channel flows. [PDF]

Sci Rep
Anzani HS, Kantoush SA, Kobayashi S.
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Effects of open-channel blocking peptides in Na_V1.5 ΔKPQ. [PDF]

Biophys J
Riedersberger M, Woltereck M, Wagner PJ, Focke K, Höller S, Lampert A, Alzheimer C, Düsterhöft S, Huth T.   +8 more
europepmc   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Impact of mixed-height vegetation patches on energy loss in open-channel flow. [PDF]

Sci Rep
Yang Z, Tang X, Li F, Liu J, Wang H, Wang J, Li C, Fan B.   +7 more
europepmc   +1 more source