Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
The dynamics of capillary flow in an open-channel system featuring trigger valves. [PDF]
Tokihiro JC +9 more
europepmc +1 more source
Classical hydrodynamics for analogue space-times: open channel flows and thin films. [PDF]
Rousseaux G, Kellay H.
europepmc +1 more source
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano +11 more
wiley +1 more source
Open-Channel Droplet Microfluidic Platform for Passive Generation of Human Sperm Microdroplets. [PDF]
Nicholson TM +9 more
europepmc +1 more source
Under oil open-channel microfluidics empowered by exclusive liquid repellency. [PDF]
Li C +7 more
europepmc +1 more source
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu +10 more
wiley +1 more source
Benchmark of computational hydraulics models for open-channel flow with lateral cavities. [PDF]
Ouro P +8 more
europepmc +1 more source
Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
Evaluation and optimal width ratio selection of microbial mineralization technique in the repair of lining cracks in Xinjiang desert open channel. [PDF]
Wang J, Zhu J, Li Y, Zhang S, Feng C.
europepmc +1 more source

