Results 91 to 100 of about 2,931,165 (316)
A working model for cytoplasmic assembly of H/ACA snoRNPs
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley +1 more source
Background: Numerous national health intervention campaigns, e.g. supplementary immunization campaigns/activities (SIAs), have been conducted in low- and middle-income countries (LMIC) in the last decades. These campaigns are rarely evaluated for overall
Sebastian Nielsen+3 more
doaj +1 more source
Data dictionaries in open system communication [PDF]
Peter B. Hitchcock
openalex +1 more source
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer+10 more
wiley +1 more source
Summaries of data on and lists of references to metallic and selected nonmetallic mineral occurrences in the Teller quadrangle, Alaska: Supplement to Open-file report 75-587: Part B, lists of references to January 1, 1980 [PDF]
Edward Huntington Cobb
openalex +1 more source
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican+7 more
wiley +1 more source
Summaries of data on and lists of references to metallic and selected nonmetallic mineral occurrences in the Ambler River quadrangle, Alaska: Supplement to Open-File Report 75-628, part A — Summaries of data to January 1, 1981 [PDF]
Edward Huntington Cobb+1 more
openalex +1 more source
Open data is the practice of making underlying research data publicly available, accessible and reusable with minimal restrictions.
Higman, Rosie+2 more
openaire +2 more sources
Novel and unscrutinized immune entities of the zebrafish gut
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil+5 more
wiley +1 more source