Results 101 to 110 of about 4,429,139 (309)

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

M3: using mask-attention and multi-scale for multi-modal brain MRI classification

open access: yesFrontiers in Neuroinformatics
IntroductionBrain diseases, particularly the classification of gliomas and brain metastases and the prediction of HT in strokes, pose significant challenges in healthcare.
Guanqing Kong   +10 more
doaj   +1 more source

Linked Open Data - De vijf sterren van open data

open access: yesInformatie Professional, 2014
Article (in Dutch) published in Informatieprofessional magazine, 2014, issue 2. Verschenen in Informatieprofessional, jaargang 2014, nummer 2.
openaire   +2 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

The effectiveness of the Fracture Risk Evaluation Model (FREM) in predicting major osteoporotic fractures and hip fractures: A register-based cohort study

open access: yesBone Reports, 2020
Michael Kriegbaum Skjødt   +6 more
doaj   +1 more source

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