Results 121 to 130 of about 11,640,166 (343)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Open data, open science, open innovation

, 2020
Support knowledge sharing about health, evolution and functioning of Mediterranean basin’s marine and coastal ecosystems with researchers, public policy makers and private sector to ensure the preservation of the basin’s resources, develop sustainable activities, control pressures and anticipate the responses to global change.
Cadiou, Jean-François, Aldo, Drago, Baris, Salihoglu   +2 more
openaire   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Open Data—Linked Data—Linked Open Data—Linguistic Linked Open Data (LLOD): A General Introduction [PDF]

, 2020
Chiarcos, Christian, Pareja-Lora, Antonio   +1 more
openaire   +2 more sources

Eculizumab monotherapy for NMOSD: Data from PREVENT and its open-label extension [PDF]

, 2021
Sean J. Pittock, Kazuo Fujihara, Jacqueline Palace, Achim Berthele, Ho Jin Kim, Celia Oreja‐Guevara, Ichiro Nakashima, Michael Levy, Shulian Shang, Marcus Yountz, Larisa Miller, Róisín Armstrong, Dean M. Wingerchuk, the PREVENT Study Group   +13 more
openalex   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

A polytopic approach to democratising decision-making on health data reuse in the European Union

Data & Policy
In our digital world, reusing data to inform: decisions, advance science, and improve people’s lives should be easier than ever. However, the reuse of data remains limited, complex, and challenging. Some of this complexity requires rethinking consent and
Anna Colom, Marta Poblet
doaj   +1 more source

Linked Open Data - De vijf sterren van open data

Informatie Professional, 2014
Article (in Dutch) published in Informatieprofessional magazine, 2014, issue 2. Verschenen in Informatieprofessional, jaargang 2014, nummer 2.
openaire   +2 more sources

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

The effectiveness of the Fracture Risk Evaluation Model (FREM) in predicting major osteoporotic fractures and hip fractures: A register-based cohort study

Bone Reports, 2020
Michael Kriegbaum Skjødt, Sören Möller, Mette Bliddal, Nana Hyldig, Jens Søndergaard, Bo Abrahamsen, Katrine Hass Rubin   +6 more
doaj   +1 more source