Results 241 to 250 of about 11,640,166 (343)

National trends in dental sedation and general anesthesia in Japan before and during the COVID-19 pandemic: a descriptive epidemiological study using National Database Open Data Japan. [PDF]

J Dent Anesth Pain Med
Nitta Y, Sasaki K, Onodera M, Takagi R, Kudo Y, Shibuya M, Kido K.   +6 more
europepmc   +1 more source

Open Data in Science

, 2008
Peter Murray‐Rust
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

A novel blockchain-based clustering model for linked open data storage and retrieval. [PDF]

Sci Rep
Fateminasab SS, Bahrepour D, Tabbakh SRK.   +2 more
europepmc   +1 more source

Experimental data on load test and performance parameters of a LENZ type vertical axis wind turbine in open environment condition

, 2017
S. Seralathan, T. Micha Premkumar, Mohammed Sohail, T. Mohan, V. Hariram   +4 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Exploring environmental risk in soils: Leveraging open data for non-sampling assessment? [PDF]

Heliyon
Aparisi-Navarro S, Moncho-Santonja M, Defez B, Candeias C, Rocha F, Peris-Fajarnés G.   +5 more
europepmc   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

An open retail boundary dataset for South Korea using open data and computer vision technique. [PDF]

Sci Data
Jeong B, Song J, Kim Y.
europepmc   +1 more source

Opening up: open access publishing, data sharing, and how they can influence your neuroscience career

, 2016
Tara L. Spires‐Jones, Panayiota Poirazi, Matthew S. Grubb   +2 more
openalex   +1 more source