Results 241 to 250 of about 11,122,566 (354)

Open Data [PDF]

, 2020
Tim Davies, Ania Calderon
openaire   +1 more source

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

Molecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita, Varda Shoshan‐Barmatz   +1 more
wiley   +1 more source

Accelerating AI for science: open data science for science. [PDF]

R Soc Open Sci
Lawrence ND, Montgomery J.
europepmc   +1 more source

Understanding chronic pain in the ubiquitous community: the role of open data. [PDF]

Front Pain Res (Lausanne), 2023
Monaco F, Georgiadis E, Chatsiou K, Bonacaro A.   +3 more
europepmc   +1 more source

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source

An open data for imaging acute aerobic exercise effects on brain and mind in emerging adulthood. [PDF]

Sci Data
Ge LK, Gao P, Chang D, Nie JJ, Wang YS, Zuo XN, Wei GX.   +6 more
europepmc   +1 more source

Open data for COVID-19 policy analysis and mapping. [PDF]

Sci Data, 2023
Katz R, Toole K, Robertson H, Case A, Kerr J, Robinson-Marshall S, Schermerhorn J, Orsborn S, Van Maele M, Zimmerman R, Stevens T, COVID AMP Coding Team, Phelan A, Carlson C, Graeden E.   +14 more
europepmc   +1 more source

DEVELOPMENT OF WEB SYSTEM TO OPEN SEISMIC OBSERVATION DATA OF BUILDINGS(Disaster)

, 2003
Hiroaki Kojima, Nobuo Fukuwa, Jun TOBITA, Masaru Nakano   +3 more
openalex   +2 more sources

Peripheral blood leukocyte signatures as biomarkers in relapsed ovarian cancer patients receiving combined anti‐CD73/anti‐PD‐L1 immunotherapy in arm A of the NSGO‐OV‐UMB1/ENGOT‐OV30 trial

Molecular Oncology, EarlyView.
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric, Annika Auranen, Katrin Kleinmanns, René DePont Christensen, Liv Cecilie Vestrheim Thomsen, Cara Ellen Wogsland, Emmet McCormack, Johanna Mäenpää, Kristine Madsen, Karen Stampe Petersson, Mansoor Raza Mirza, Line Bjørge   +11 more
wiley   +1 more source

How will we prepare for an uncertain future? The value of open data and code for unborn generations facing climate change. [PDF]

Proc Biol Sci
Gomes DGE.
europepmc   +1 more source