Results 61 to 70 of about 853,817 (299)

Something for everyone? The different approaches of academic disciplines to Open Educational Resources and the impact on widening participation

Journal of Open, Flexible and Distance Learning, 2011
This article explores the relationship between academic disciplines’ representation in the United Kingdom Open University’s (OU) OpenLearn open educational resources (OER) repository and in the OU’s fee-paying curriculum.
Tony Coughlan, Leigh-Anne Perryman
doaj   +2 more sources

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Implementing A Naïve Bayes Classifier on Iris Data Using MATLAB, A Classification Method by Using Grid Parameters Optimization

Wasit Journal for Pure Sciences
Data mining categorization is crucial for predicting outcomes. Naive Bayes Classification (NBC) is a prominent approach used in data mining for classification purposes. It has the ability to anticipate outcomes and is generally more efficient than other
Mohammed Hasan, Asmaa ali
doaj   +1 more source

The Shift Toward Openness in Education and the Implications for Learning Ecosystems and Ecologies [PDF]

, 2023
Aras Bozkurt, Christian M. Stracke
openalex   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Using an open-ended socio-technical design challenge for entrepreneurship education in a first-year engineering course [PDF]

, 2023
Jan DeWaters, Bhavana Kotla
openalex   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Predicting open education competency level: A machine learning approach. [PDF]

Heliyon, 2023
Ibarra-Vazquez G, Ramírez-Montoya MS, Buenestado-Fernández M, Olague G.   +3 more
europepmc   +1 more source