Results 81 to 90 of about 2,077,918 (304)
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Open Praxis, volumen 0 issue 1
Table of Contents - Providing Effective Feedback Online Zane Berge & Mauri Collins (1-10) - Mobile Technologies and the Future of Global Education Rory McGreal (11-16) - Cross-Border Higher Education through E-Learning: Issues and Opportunities ...
Open Praxis, Editor, Editor Open Praxis
core +1 more source
ENOEL WS#1 - Embrace the Open: An Introduction to Open Textbooks
<p>SPARC Europe’s European Network of Open Education Librarians (https://sparceurope.org/what-we-do/open-education/enoel/) organises a series of Workshops entitled “Embrace the Open” to learn collaboratively about some key ...
European Network of Open Education Librarians
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Recull d'experiències sobre Open Education a la UOC
Recull de les experiències al voltant dels Open Education (OE) i Open Educational Resources (OER) a la UOC.Recopilación de las experiencias sobre Open Education (OE) y Open Educational Resources (OER) en la UOC.Compilation of experiences on Open ...
Minguillón Alfonso, Julià
core
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Scaling the Unscalable? Interaction and Support in Open Online Education [PDF]
As part of the SOONER project supported by the Netherlands Initiative for Education Research (NRO), The Netherlands Organisation for Scientific Research (NWO), and the Dutch Ministry of Education, Culture and Science [grant number 405-15-705]
Kasch, J.A.
core
Recognizing the vital role that teachers play in shaping student engagement through the use of technology, this study investigates the intentions of mathematics teachers to employ technology-driven cognitive engagement strategies. Specifically, the study
Robert Weinhandl +6 more
doaj +1 more source

