Results 91 to 100 of about 28,093,260 (257)

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

SCHEV Open Virginia Advisory Committee (OVAC) Webinar Series Part IV: Open Education: Student Success and Faculty Autonomy: Listening to OER Stakeholders in Virginia

, 2021
This presentation will discuss Virginia OER stakeholder interviews conducted by SPARC Open Education Leadership Program participants, Judy Thomas (UVA; 2019-2020 SPARC Open Education Leadership Cohort) and Sophie Rondeau (VIVA; 2020-2021 SPARC Open ...
Thomas, Judith, Rondeau, Sophie, Rebar, Beverly, Ghaphery, Jimmy   +3 more
core  

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Transformative Sustainability-Oriented Open Education

, 2020
How can open education play a role in making academia more responsive and responsible in addressing ill-defined and ambiguous, but ever so urgent, sustainable development challenges? In this chapter, a case study from the field of sustainable development
Algers, Anne,, Wals, Arjen E.J., Algers, Anne   +2 more
core   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

OER Adaptation and Reuse across cultural contexts in Sub Saharan Africa: Lessons from TESSA (Teacher Education in Sub Saharan Africa)

Journal of Interactive Media in Education, 2012
Over a period of three years a number of International and African based institutions collaborated to design and create a set of Open Educational Resources (OERs) to support school based teacher education as part of the TESSA project.
Freda Wolfenden, Alison Sarah Hemmings Buckler, Fred Keraro   +2 more
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

What can functional transcranial Doppler ultrasonography reveal about the cerebral lateralization of writing

FEBS Letters, EarlyView.
Which brain hemisphere controls writing? This review synthesizes all five functional transcranial Doppler studies of writing (handwriting and typing) published to date in adults and children. Right‐handers show left‐hemispheric dominance for the linguistic component of writing (written word generation), whereas findings for left‐handers remain ...
Marietta Papadatou‐Pastou
wiley   +1 more source

Something for everyone? The different approaches of academic disciplines to Open Educational Resources and the impact on widening participation

Journal of Open, Flexible and Distance Learning, 2011
This article explores the relationship between academic disciplines’ representation in the United Kingdom Open University’s (OU) OpenLearn open educational resources (OER) repository and in the OU’s fee-paying curriculum.
Tony Coughlan, Leigh-Anne Perryman
doaj   +2 more sources

Technology integration in physics education: using teachers’ age, gender, and teaching experience to explore differences in cognitive engagement strategies

Cogent Education
The increasingly important role of technology underscores the need for students to acquire 21st-century skills, including a deep understanding of science.
Jonas Mayrhofer, Selina Baldinger, Branko Anđić, Viktoria Riegler, Robert Weinhandl   +4 more
doaj   +1 more source