Results 101 to 110 of about 6,217,103 (344)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Implementing A Naïve Bayes Classifier on Iris Data Using MATLAB, A Classification Method by Using Grid Parameters Optimization

open access: yesWasit Journal for Pure Sciences
Data mining categorization is crucial for predicting outcomes. Naive Bayes Classification (NBC) is a prominent approach used in data mining for classification purposes. It has the ability to anticipate outcomes and is generally more efficient than other
Mohammed Hasan, Asmaa ali
doaj   +1 more source

Beginning Teachers’ Motivations and Aspirations through Teacher Education [PDF]

open access: yes, 2007
: Much research has focused on what motivates people to take on a teaching career. An open question remains – how do their motivations and aspirations change through their professional education? We sampled secondary teacher education candidates near the
Basikin, Basikin   +2 more
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

The use of open education resources in higher education programmes of academic practice

open access: yes, 2012
Digital technologies provide a wide range of tools which research shows can enhance and support teaching and learning. However, this knowledge is not uniformly available across disciplines.
Bradshaw, Pete   +2 more
core  

Composing Possibilities: Open Educational Resources and K-12 Music Education [PDF]

open access: yes, 2013
Music open educational resources (OER) have the potential to fill gaps in access to instructional materials for K-12 music teachers and learners, and to support teachers and learners as content creators and collaborators in meeting educational goals ...

core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Open Online Courses in Public Health: experience from Peoples-uni [version 1; referees: 1 approved, 2 approved with reservations]

open access: yesF1000Research, 2017
Open Online Courses (OOCs) are offered by Peoples-uni at http://ooc.peoples-uni.org to complement the courses run on a separate site for academic credit at http://courses.peoples-uni.org.
Richard F. Heller   +4 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

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