Results 51 to 60 of about 1,948,813 (330)

Designing Open Educational Resources through Knowledge Maps to enhance Meaningful learning [PDF]

, 2008
This paper demonstrates some pedagogical strategies for developing Open Educational Resources (OERs) using the knowledge mapping tool Compendium. It also describes applications of Knowledge Maps to facilitate meaningful learning by focusing on specific ...
Connolly, Teresa, Okada, Alexandra
core   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

STEM@1000mph: developing open educational resources in a live engineering project [PDF]

, 2013
Higher education institutions are recognising the clear benefits of open educational resources, and academics are engaging with the development of these resources.
Drew, Ben, Howard, Yvonne, Johns, Dan, Lanham, John   +3 more
core   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Sharing Resources in Open Educational Communities

Qualitative Research in Education, 2014
The spread of Internet and the latest Web developments have facilitated the connection between teachers, learners and institutions, as well as the creation and sharing of new open educational resources (OERs).
Paolo Tosato, Beatriz Carramolino Arranz, Bartolomé Rubia Avi   +2 more
doaj   +2 more sources

Open Educational Resources and Practices [PDF]

, 2008
In the last few years, Open Educational Resources (OER) have gained much attention. From January 2006 to December 2007 the Open e-Learning Content Observatory Services (OLCOS), a project co-funded by the European Commission under the eLearning Programme,
Guntram Geser, Sandra Schaffert
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Something for everyone? The different approaches of academic disciplines to Open Educational Resources and the impact on widening participation

Journal of Open, Flexible and Distance Learning, 2011
This article explores the relationship between academic disciplines’ representation in the United Kingdom Open University’s (OU) OpenLearn open educational resources (OER) repository and in the OU’s fee-paying curriculum.
Tony Coughlan, Leigh-Anne Perryman
doaj   +2 more sources

Editorial - JIME OER13 special issue: The potential of openness for engaging communities

Journal of Interactive Media in Education, 2013
This special issue is the fourth devoted to Open Educational Resources (OER) and the third to be drawn from papers presented at the main annual UK-based OER conference.
Andy Lane, Anna Comas-Quinn, Jackie Carter   +2 more
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source