Results 111 to 120 of about 30,557,565 (303)

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

open access: yesFEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés   +2 more
wiley   +1 more source

Investigation into voltage and process variation-aware manufacturing test

open access: yes, 2009
Increasing integration and complexity in IC design provides challenges for manufacturing testing. This thesis studies how process and supply voltage variation influence defect behaviour to determine the impact on manufacturing test cost and quality.
Ingelsson, Bo Urban
core   +1 more source

Effect of atomoxetine on hyperactivity in the open field test.

open access: yes, 2014
Upper: Pre-open field test. Lower: Open field test for experimental periods. (□) Control group, (○) SHR group, (Δ) SHR and 0.25 mg/kg atomoxetine-treatd group, (•) SHR and 0.5 mg/kg atomoxetine-treatd group, () SHR and 1 mg/kg atomoxetine-treatd group. *
Juhee Han (637640)   +5 more
core   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Evaluation of behavioral responses to restraint stress in the house mouse (Mus musculus musculus) of wild origin

open access: yesBioscience Journal
Stress is a fundamental concept for many areas of animal research. In laboratory rodents, exposure to various stressors results in immediate and postponed behavioral changes that can be measured with standard tests.
Maria A. Klyuchnikova
doaj   +1 more source

Verfahrensdokumentation für GEB-50: General Ecological Behavior Scale

open access: yes, 2020
Die GEB-Skala erfasst die individuelle Umwelteinstellung, welches in der Forschung und im Bereich der Verhaltenssteuerung Einsatz findet. Sie geht aus der aus 40 Items bestehenden Guttmann-Skala von Fejer (1978) hervor. Eine zuvor auf 65 Items erweiterte
Kaiser, F. G.
core   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

open access: yesFEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini   +3 more
wiley   +1 more source

Exploring the Impact of Semaglutide on Cognitive Function and Anxiety-Related Behaviors in a Murine Model of Alzheimer’s Disease

open access: yesBiomedicines
Background: Alzheimer’s disease (AD), the most prevalent form of dementia, is characterized by progressive cognitive decline and behavioral disturbances, with an increasing incidence as the global population ages.
Ianis Kevyn Stefan Boboc   +4 more
doaj   +1 more source

Sex differences in the elevated plus-maze test and large open field test in adult Wistar rats. [PDF]

open access: yesPharmacol Biochem Behav, 2021
Knight P   +5 more
europepmc   +1 more source

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