Results 71 to 80 of about 30,557,565 (303)

Social Isolation Induces Sex‐Specific Differences in Behavior and Gut Microbiota Composition in Stress‐Sensitive Rats

Brain and Behavior
Background Social isolation (SI) is an established rat model of chronic stress. We applied this to the stress‐sensitive Wistar Kyoto (WKY) strain to explore brain‐to‐gut interactions associated with mood.
Charlotte Hurst, Gosia Zobel, Wayne Young, Trent Olson, Nabil Parkar, Jeremy Bracegirdle, Rina Hannaford, Rachel C. Anderson, Julie E. Dalziel   +8 more
doaj   +1 more source

Kefir enhances stress resilience and mitigates PTSD-related behavioral and hematological changes in mice

Frontiers in Physiology
Post-traumatic stress disorder (PTSD) is a complex psychiatric condition characterized by behavioral, cognitive, immunological, and neurochemical disturbances following traumatic experiences.
Vitalii A. Balatskyi, Tetiana R. Dmytriv, Tetiana R. Dmytriv, Andrii Divnych, Volodymyr I. Lushchak, Volodymyr I. Lushchak   +5 more
doaj   +1 more source

test

, 2023
testtes
test, test
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Continuous OFT-Based Behavioral Phenotyping Reveals Neural Stem Cell-Associated Shifts in Depression-like Mice

Brain Sciences
Background: Depression-like phenotypes in animal models often show graded behavioral variation rather than uniform group-wise changes, yet treatment effects are still commonly evaluated using categorical comparisons.
Han Wang, Zhaoming Liu, Xianjie Li, Lin Fu, Tingxin Lu, Dantong Wang, Guanzhen Lin, Caixia Wu   +7 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Verfahrensdokumentation für BIFA-AL: Biographischer Fragebogen für Alkoholabhängige

, 2006
Der BIFA-AL dient primär der differentialpsychologischen Erhebung von biographischen Daten von Alkoholabhängigen auf der Basis von Forschungsergebnissen zur ätiologischen und kausalen Entwicklung des Vollbildes der Suchtkrankheit "Alkoholismus" (gemäß ...
Bühler, K.-E., Bardeleben, H.
core   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Disease-specific monoclonal antibodies targeting glutamate decarboxylase impair GABAergic neurotransmission and affect motor learning and behavioral functions

Frontiers in Behavioral Neuroscience, 2015
Autoantibodies to the smaller isoform of glutamate decarboxylase can be found in patients with type 1 diabetes and a number of neurological disorders, including stiff-person syndrome, cerebellar ataxia and limbic encephalitis.
Mario U Manto, Jerome eHonorat, Christiane Susanne Hampe, Rafael eGuerra-Narbona, Juan Carlos eLópez Ramos, José M Delgado-García, Fumihito eSaitow, Hidenori eSuzuki, Yuchio eYanagawa, Hidehiro eMizusawa, Hiroshi eMitoma   +10 more
doaj   +1 more source