Results 41 to 50 of about 16,607,492 (282)

Management of open globe injury: a narrative review. [PDF]

Eye (Lond)
AbstractOpen globe injuries are a significant global cause of visual loss, including unilateral and bilateral blindness. Prognosis is predicted by injury severity, with lower presenting visual acuity and more posterior injuries associated with poor visual outcomes, although even the most severely injured eyes with no perception of light vision may ...
Blanch RJ, McMaster D, Patterson TJ.
europepmc   +3 more sources

Perfluoro-n-octane mimicking an intraocular foreign body

GMS Ophthalmology Cases, 2017
Retained intraocular foreign body (IOFB) is a major cause of visual loss following open globe injuries. Detecting the presence and accurate localization of IOFB in the setting of an open globe injury remains a challenge.
Baskaran, Prabu, Ganne, Pratyusha, Krishnappa, Nagesha C   +2 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

A series of 777 pellet gun ocular injuries over a 4-month period in Kashmir

Indian Journal of Ophthalmology, 2022
Purpose: To examine the incidence, clinical findings and management of pellet gun–related ocular injuries that occurred during protests in Kashmir region.
Xin Wei, Bryan Chin Hou Ang, Arshi Nazir, Faisal Qayoom Shah, Tariq Qureshi, Astha Jain, Sundaram Natarajan   +6 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Open Globe Injuries: Review of Evaluation, Management, and Surgical Pearls

Clinical Ophthalmology, 2022
Yujia Zhou,1 Mark DiSclafani,2 Lauren Jeang,1 Ankit A Shah1 1Department of Ophthalmology, University of Florida College of Medicine, Gainesville, FL, USA; 2Department of Ophthalmology, University of South Florida Morsani College of Medicine, Tampa, FL ...
Zhou Y, DiSclafani M, Jeang L, Shah AA
doaj  

Epidemiologic and Clinical Features of Open-Globe Injuries in Childhood

, 2012
Pur po se: To evaluate the epidemiologic and clinical features of open-globe injuries in childhood. Ma te ri al and Met hod: The records of the pediatric patients who were evaluated for open-globe injuries between 2007 and 2011 in our department were ...
Yaylalı, Volkan, Avni Murat Avunduk, Kaşıkçı, Alper, Volkan Yaylalı, Cem Yıldırım, Avunduk, Avni Murat, Çetin, Ebru Nevin, Ebru Nevin Çetin, Gülden Saraç, Alper Kaşıkçı, Yıldırım, Cem, Saraç, Gülden   +11 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Microbial contamination in open globe injury

Nepalese Journal of Ophthalmology, 1970
Introduction: Endophthalmitis is the most dreaded complication of ocular trauma and knowledge of the microbial contaminants is essential to start empirical antibiotic therapy. Purpose: To determine incidence of contamination after open globe injuries (OGI) in our setup and to identify the spectrum of microorganisms contaminating open globe injuries ...
S, Bhala, S, Narang, S, Sood, C, Mithal, S K, Arya, V, Gupta   +5 more
openaire   +3 more sources