Results 61 to 70 of about 160,008 (304)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Remarkable visual recovery after severe open globe injury

open access: yesAmerican Journal of Ophthalmology Case Reports, 2016
Purpose: To describe a case of remarkable visual recovery after severe open globe injury. Observations: We present a case of a 70-year-old man with an open globe injury with no light perception vision before and after primary repair of his ruptured globe
Yewlin E. Chee   +2 more
doaj   +1 more source

Lighting the Farm Home [PDF]

open access: yes, 1940
PDF pages ...
Biebricher, Anne, Blauser, I. P.
core  

Warmblood fragile foal syndrome type 1 mutation (PLOD1 c.2032G>A) is not associated with catastrophic breakdown and has a low allele frequency in the Thoroughbred breed. [PDF]

open access: yes, 2020
BackgroundCatastrophic fractures are among the most common cause of fatalities in racehorses. Several factors, including genetics, likely contribute to increased risk for fatal injuries.
Arthur, R   +6 more
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

EYE TRAUMA. OPEN GLOBE INJURY MANAGEMENT

open access: yesZdravniški Vestnik, 2004
Background. Ocular trauma is important cause of blindness. Birmingham Eye Trauma Terminology allows us to use a standardized eye injury terminology which permits an unambigous interpretation.
Mojca Globočnik Petrovič
doaj  

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

PATTERN OF OCULAR TRAUMA IN BENGAHZI EYE HOSPITAL BENGAHZIS – LIBYA

open access: yesLibyan International Medical University Journal, 2017
Background   This  study  was  conducted  to  determine  the  pattern  of ocular trauma  in  Benghazi- Libya . Methods   All  cases  of  ocular  trauma  admitted  to  Benghazi  eye hospital  from January  2011  to  August  2012  were  retrospectively ...
mariam m gebril
doaj  

An unusual cause of globe rupture in a child and its management

open access: yesTNOA Journal of Ophthalmic Science and Research, 2018
Globe rupture in children usually occurs from injury with sharp objects. Our patient had a pungai (Indian beech tree) seed thrown at his right eye and presented with ruptured globe.
Anand Ravi Kumar   +2 more
doaj   +1 more source

Challenges and Solutions for Functional Neurosurgery in Developing Countries. [PDF]

open access: yes, 2018
Functional neurosurgery techniques remain integral to the neurosurgical treatment armamentarium but data on global implementation remains scarce. In comparison to high-income countries (HIC), low- and middle-income countries (LMIC) suffer from an ...
Fezeu, Francis   +5 more
core  

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