Results 81 to 90 of about 841,980 (298)

Effect of biofeedback – therapy on clinical semiology, quality of life and sensorimotor function of anorectal area at irritable bowel syndrome with refractory constipation

open access: yesРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии, 2014
Aim of investigation. To estimate effect of biofeedback-therapy (BFT) on clinical symptoms, quality of life, sensorimotor function of anorectal area at irritable bowel syndrome (IBS) with refractory constipation (IBS-C).Material and methods.
O. V. Krapivnaya
doaj  

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

The power of partnership in open government: reconsidering multistakeholder governance reform

open access: yes, 2022
What the Open Government Partnership tells us about how international initiatives can and do shape domestic public sector reform. At the 2011 meeting of the UN General Assembly, the governments of eight nations—Brazil, Indonesia, Mexico, Norway ...
Ingrams, Alex   +2 more
core   +1 more source

Open Government in Spain: An Introspective Analysis

open access: yesAdministrative Sciences
In recent years, there has been an increasing amount of research analyzing open government initiatives that enable access to the information held by public bodies, promoting accountability and the fight against corruption.
Ricardo Curto-Rodríguez   +2 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Digital Government and Open Data Readiness Assessment

open access: yes, 2019
This report, composed of two separate themes of Digital Government Readiness Assessment (DGRA) and Open Data Readiness Assessment (ODRA), is intended to help government assess their digital environments and frame ...
Government of Vietnam, World Bank
core   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

open access: yesFEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino   +2 more
wiley   +1 more source

Exploring the Impact of Adopting Open Data in the UK Government

open access: yes, 2012
A new kind of activity – fuelled by the capabilities that not only modern Web technologies offer, but also as a change in social practices and expectations – has recently become the centre of much attention and discussion; it involves the curation and ...
Ramine Tinati   +7 more
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

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