Results 61 to 70 of about 39,328,094 (290)
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Data quality, government data and the open data infosphere
This paper discusses ways in which the environment in which data are released affects data quality. Using the example of the release of open government data into an information market populated by open data, a basic assumption of open data, that eyeballs
O'Hara, Kieron
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
OGD2011 – Requirements Analysis for an Open Data Strategy (in Austria)
Part 2: eEnvironment and Cross-Border Services in Digital Agenda for EuropeInternational audienceThe OGD2011 project launches the 1st Open Government Data Conference Austria and brings together international and national experts in the area of Open ...
Kaltenböck, Martin, Martin Kaltenböck
core +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Modern agriculture faces critical challenges, including climate change induced water shortage, inefficient resource utilization, and reducing soil health which reduce sustainability and reduce crop yields. Traditional farming methods, dependent on manual
Ayesha Khaliq +6 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Publishers Working with Open Government Data: A Work Framework
This paper presents an Open Government Data (OGD) publisher framework, with work roles, field of work, and environmental descriptions. Previous knowledge about publishers' work is fragmented, with gaps and variations, indicating a high level of ...
Jonathan Cruose +6 more
core +1 more source
The openness of government data is considered essential and is an influential innovation in society to prevent corruption by increasing the transparency of information and data.
Herma Adis, Catur Apriono
doaj +1 more source

