Results 61 to 70 of about 18,200,732 (302)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Morbidity is related to a green living environment [PDF]

, 2009
Background: As a result of increasing urbanisation, people face the prospect of living in environments with few green spaces. There is increasing evidence for a positive relation between green space in people's living environment and self-reported ...
Vries, S., de, de Vries, S.T., Schellevis, F.G., Vries, S. de, R A Verheij, de Vries, S., Verheij, R.A., Vries, S.T. de, Groenewegen, P.P., J Maas, P P Groenewegen, Spreeuwenberg, P., Maas, J., P Spreeuwenberg, Verheij, R., S de Vries, F G Schellevis   +16 more
core   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Green Open Space Priority Modelling Using GIS Analysis in West Jakarta

Indonesian Journal of Geography, 2022
Green open space is one of the most important land uses, especially in densely populated urban areas. Public Green Open Land in each area regulated in Law No. 1 of 2007 is at least 20%.
Prama Ardha Aryaguna, Ghefra Rizkan Gaffara, Dayu Ariesta Kirana Sari, Ade Arianto   +3 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Environmental Impacts of Green Open Space in Urban Indonesia: A Difference-in-Differences Analysis

Asian Development Review
This study investigates the impact of green open spaces in reducing the probability of flooding and open waste burning in urban areas in Indonesia’s three largest metropolitan cities: Surabaya, Jakarta, and Medan.
ILMIAWAN AUWALIN, RUMAYYA, NI MADE SUKARTINI   +2 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

The Use of Vertical Gardens as a Network of Urban Navigation Elements with a Positive Impact on Biodiversity and Microclimate in a Dense Urban Environment

Slovak Journal of Civil Engineering, 2023
Horizontal green areas are becoming valuable, yet extruded spots, and their constant elimination at the expense of commercial and housing developments is disrupting green infrastructure. Interlocked existing urban structures seldom allow for the creation
Zaťovičová Miriam, Majorošová Martina   +1 more
doaj   +1 more source

Green Open Space Functions in Kauman Area, Semarang City, Indonesia

Journal of Architectural Design and Urbanism, 2020
Based on the results of identification and analysis related to the functions of green open space in Kelurahan Kauman, both private and public green open space, it was found that private green open space located in residential areas, office areas, education area, and in the worship area.
Intan Muning Harjanti, Pratamaningtyas Anggraini   +1 more
openaire   +2 more sources