Results 121 to 130 of about 21,603,813 (294)

Open and green areas Soma (Manisa) district determining potential [PDF]

, 2010
Fen Bilimleri Enstitüsü, Peyzaj Mimarlığı Ana Bilim DalıHızlı kentleşme, sanayileşme ve artan nüfus, mekânlarda yapılaşmaların artmasına, açık-yeşil alanların miktarının giderek azalmasına neden olmakta ve bunun sonucu kentli doğadan hızla kopmaktadır ...
Günal, İlknur
core   +1 more source

Tamagawa Tri-Area Green Map

, 2002
A map showing the Tamagawa Tri Area, along the Tama River in Tokyo. It highlights green areas, flora and fauna, and other ecological amenities.

core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Evaluation Open and Green Areas of Kayseri Urban Complex with a System Approach

Selçuk Üniversitesi Mühendislik, Bilim ve Teknoloji Dergisi, 2005
In urban environments green areas play an important part in forming good qualityenvironments with their ecological, economical, physical, social and aesthetic functions. Open and greenarea systems contribute the formation of urban communities by creating more livable environments. Inthis reseearch open and green areas have been searched in the frame of
KURTASLAN, Banu Öztürk, YAZGAN, Murat E.   +1 more
openaire   +1 more source

Open Green Area Strategies and Action Planning in Resilient Coastal Cities

Black Sea Journal of Engineering and Science
Cities, as complex entities composed of interdependent and multi-layered systems, are inherently vulnerable to both natural disasters and human-induced threats. Nevertheless, they are not only spaces exposed to adverse impacts but also strategic hubs for infrastructure, sustainability, technology, and investment.
Merve Sipahi, Şevval Bozkurt
openaire   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Green open spaces: climate mitigation of climate change in Indonesia [PDF]

Introduction: The provision of microclimate for young people is an important prerequisite for outdoor thermal comfort in urban communities. The microclimate consists of four elements: air temperature, humidity, wind speed and solar radiation.
Agus, Fadilatur Rahmi, Ismail, Yunita
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Healthy Living Harlem: green mapping for eco-justice

, 2010
A map of the Harlem neighbourhood in New York City, NY showcasing green resources and landmarks as well as problem areas such as abandoned and contaminated ...
Faith Leaders for Environmental Justice, Center for International Earth Science Information Network   +1 more
core   +1 more source