Results 111 to 120 of about 670,178 (260)

Open Green Area Strategies and Action Planning in Resilient Coastal Cities

Black Sea Journal of Engineering and Science
Cities, as complex entities composed of interdependent and multi-layered systems, are inherently vulnerable to both natural disasters and human-induced threats. Nevertheless, they are not only spaces exposed to adverse impacts but also strategic hubs for infrastructure, sustainability, technology, and investment.
Merve Sipahi, Şevval Bozkurt
openaire   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Evaluation Open and Green Areas of Kayseri Urban Complex with a System Approach

Selçuk Üniversitesi Mühendislik, Bilim ve Teknoloji Dergisi, 2005
In urban environments green areas play an important part in forming good qualityenvironments with their ecological, economical, physical, social and aesthetic functions. Open and greenarea systems contribute the formation of urban communities by creating more livable environments. Inthis reseearch open and green areas have been searched in the frame of
KURTASLAN, Banu Öztürk, YAZGAN, Murat E.   +1 more
openaire   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Needs analysis for public green spaces in Grosuplje [PDF]

Urbani Izziv, 2008
A huge increase in residential and business-commercial construction has characterised Grosuplje, a young town and suburban settlement of the greater Ljubljana area, over the last two decades, thereby increasing the number of possible users of its open ...
Klara Sulič, Ana Kučan
doaj  

The effect of urban open green areas on carbon footprint

Urban open green areas are the most important component of urban planning. A city's ability to live in a philosophy that is compatible with ecological principles and takes into account natural processes depends on the correct planning of open green areas.
Demiroğlu, Demet, Karadağ, Aybike Ayfer, Kurtaslan, Banu Öztürk, Ermiyagil, Selen Abbasoğlu   +3 more
openaire   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source