Results 191 to 200 of about 16,705,427 (261)

Perioperative Camrelizumab and Apatinib for High‐Risk Resectable Hepatocellular Carcinoma: A Phase II Study

open access: yesMedComm, Volume 7, Issue 10, October 2026.
In this study, perioperative camrelizumab plus apatinib demonstrated promising efficacy and safety in resectable hepatocellular carcinoma (HCC) patients at high risk of recurrence, achieving a major pathological response of 46.2%. The median disease‐free survival and progression‐free survival were 24.1 months and 18.3 months, respectively.
Yunlong Cui   +13 more
wiley   +1 more source

Initial Experience of Laparoscopic Hepatectomy for Intrahepatic Duct (IHD) Stones: Comparison with Open Hepatectomy

open access: yesThe Journal of Minimally Invasive Surgery, 2014
Joon Sang Lee   +2 more
openaire   +2 more sources

Hippo Pathway–YAP/TAZ Signaling: Molecular Mechanisms, Biological Function, Diseases, and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 10, October 2026.
The Hippo–YAP/TAZ–TEAD pathway integrates mechanical and biochemical cues to govern organ growth, regeneration, cancer, and fibrosis. This review dissects pathway physiology, TEAD structural pharmacology and ligandable pockets, and therapeutic strategies spanning palmitoylation‐pocket inhibitors, PROTAC degraders, and gene/RNA therapies, highlighting ...
Xiaodan Qu, Zhan‐you Wang
wiley   +1 more source

Liver Metastases from Colorectal Cancer: From Pathogenesis to Current Treatment

open access: yesMedComm, Volume 7, Issue 10, October 2026.
The liver is not merely a passive recipient of disseminated tumor cells, but a unique metastatic organ shaped by anatomical, metabolic, and immunological characteristics that support tumor colonization. Increasing evidence indicates that colorectal cancer liver metastasis development is driven by dynamic interactions between tumor intrinsic programs ...
Jialiang Fan   +10 more
wiley   +1 more source

Multifunctional Hydrogels: Rational Design and Application in Regenerative Medicine

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Multifunctional hydrogels represent a paradigm shift in regenerative medicine, integrating rational material design with bioactive functionality to address complex tissue repair challenges. This review systematically examines the molecular engineering, structure–function relationships, and translational landscape of advanced hydrogel systems, spanning ...
Linyang Song   +4 more
wiley   +1 more source

Antiviral Therapy and Post‐Resection Outcomes in Patients With Hepatitis B Virus‐Related Hepatocellular Carcinoma

open access: yesAlimentary Pharmacology &Therapeutics, Volume 64, Issue 8, Page 1123-1134, October 2026.
In 902 patients with HBV‐related HCC undergoing curative resection, antiviral regimens (ETV, TDF, TAF) showed comparable recurrence‐free survival. However, TDF was independently associated with improved overall survival compared with ETV. ABSTRACT Background & Aims The comparative outcomes of entecavir (ETV), tenofovir disoproxil fumarate (TDF), and ...
Jaehong Jeong   +10 more
wiley   +1 more source

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