Results 21 to 30 of about 2,286,604 (339)

Annexin A5 Increases Survival in Murine Sepsis Model by Inhibiting HMGB1-Mediated Proinflammation and Coagulation

open access: yesMolecular Medicine, 2016
The identification of HMGB1 as a late mediator in sepsis has highlighted HMGB1 as a promising therapeutic target for sepsis treatment. Recent studies have revealed that annexin A5, a 35 kDa Ca2+-dependent phospholipid binding protein, exerts ...
Jung Hwa Park   +10 more
doaj   +1 more source

Wie Crowdsourcing neue Forschungsansätze liefert. "Reden Sie mit!" – Ein Innovationsprojekt der Ludwig Boltzmann Gesellschaft

open access: yesMitteilungen der Vereinigung Österreichischer Bibliothekarinnen und Bibliothekare, 2019
Forschung muss Nutzen stiften, insbesondere vor dem Hintergrund sozialer, ökologischer, wirtschaftlicher und politischer Problemstellungen ist die Wissenschaft gefordert gesellschaftlich relevante Fragestellungen aufzugreifen.
Lucia Malfent, Benjamin Missbach
doaj   +1 more source

One-step preparation of antimicrobial silicone materials based on PDMS and salicylic acid: insights from spatially and temporally resolved techniques

open access: yesnpj Biofilms and Microbiomes, 2021
In this work, we introduce a one-step strategy that is suitable for continuous flow manufacturing of antimicrobial PDMS materials. The process is based on the intrinsic capacity of PDMS to react to certain organic solvents, which enables the ...
Luca Barbieri   +6 more
doaj   +1 more source

Linking Circular Innovation with ‘Open Innovation’ Paradigm: A Stakeholder Approach

open access: yesCircular Economy, 2023
The paper aims to investigate how open innovations (OI) paradigm, based on the principle of the collaboration between the innovation ecosystem stakeholders can contribute to the adoption and promotion of the circular economy (CE).
Małgorzata Runiewicz-Wardyn
doaj   +1 more source

Open minds, open innovation [PDF]

open access: yesJournal of Intellectual Property Law & Practice, 2011
Not so many years ago, the term “open innovation” was unknown to the intellectual property community. While the concept existed, there was little evidence that it existed, or that it was likely to gain any currency at all, before the publication in 2003 of Henry Chesburgh’s Open Innovation: The new imperative for creating and profiting from technology.
openaire   +1 more source

Engineered adeno-associated virus 3 vector with reduced reactivity to serum antibodies

open access: yesScientific Reports, 2021
The natural serotypes of adeno-associated virus (AAV) or their variants, such as AAV8 and AAV5, are commonly used as vectors in the clinical programs for liver-targeted gene therapy.
Mika Ito   +4 more
doaj   +1 more source

Co-creating a patient and public involvement and engagement ‘how to’ guide for researchers

open access: yesResearch Involvement and Engagement, 2020
Plain language summary Research should benefit society at large. Involving citizens those who are affected by research may not only increase the quality, but can also push research towards generating greater societal benefits and relevant outcomes for ...
Raphaela E. Kaisler, Benjamin Missbach
doaj   +1 more source

"Open Innovation" and "Triple Helix" Models of Innovation: Can Synergy in Innovation Systems Be Measured? [PDF]

open access: yes, 2016
The model of "Open Innovations" (OI) can be compared with the "Triple Helix of University-Industry-Government Relations" (TH) as attempts to find surplus value in bringing industrial innovation closer to public R&D.
A Giddens   +60 more
core   +2 more sources

Label-free chemical imaging of cytochrome P450 activity by Raman microscopy

open access: yesCommunications Biology, 2022
Cytochrome P450 activity is assessed at the single-cell level using chemical imaging, Raman microscopy, which gives quantitative insights into effects of drug administration on cellular biochemistry.
Menglu Li   +5 more
doaj   +1 more source

A Taxonomy to Understand Scaling of Innovation by African Enterprises

open access: yesThe African Journal of Information and Communication, 2021
Grounded in empirical research findings and key statements in the literature, this article proposes a four-part taxonomy for mapping African knowledge-based enterprises’ efforts to achieve scale. The taxonomy, adapted from the framework proposed by Uvin
Chris Armstrong, Jeremy De Beer
doaj  

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