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Web technologies for open innovation [PDF]

Proceedings of the 3rd International Web Science Conference, 2011
The spread of the open innovation model created new challenges for further implications of the Web in making the innovation happen. In this paper we present a research on the application of the Web technologies in the open innovation model. We analyze technologies for expert search, key words matching and social propagation that would enable more ...
Jesic, Darko, Kovacevic, Jovana, Stankovic, Milan   +2 more
openaire   +3 more sources

Advancing a Typology of Open Innovation [PDF]

International Journal of Innovation Management, 2010
Interest in the concept of open innovation (OI) has increased during recent years; yet, this line of inquiry remains limited due to the lack of a more comprehensive conceptual framework. As a first step toward a unifying framework, we provide a critical review of previous research on the conceptualization, antecedents, and consequences of OI.
Gianiodis, Peter T., Ellis, S.C., Secchi, Enrico   +2 more
openaire   +4 more sources

A Taxonomy to Understand Scaling of Innovation by African Enterprises

The African Journal of Information and Communication, 2021
Grounded in empirical research findings and key statements in the literature, this article proposes a four-part taxonomy for mapping African knowledge-based enterprises’ efforts to achieve scale. The taxonomy, adapted from the framework proposed by Uvin
Chris Armstrong, Jeremy De Beer
doaj  

Annexin A5 as an immune checkpoint inhibitor and tumor-homing molecule for cancer treatment

Nature Communications, 2020
AnnexinV has been shown to bind phosphatidylserine expressed by chemotherapy-induced apoptotic cells increasing their immunogeneicity. Here, the authors demonstrate in a preclinical tumor model that fusing tumor-antigen peptide to Annexin V enhances its ...
Tae Heung Kang, Jung Hwa Park, Andrew Yang, Hyun Jin Park, Sung Eun Lee, Young Seob Kim, Gun-Young Jang, Emily Farmer, Brandon Lam, Yeong-Min Park, Chien-Fu Hung   +10 more
doaj   +1 more source

Examining iPSC derived motor neuron variability and genome stability monitoring as a solution

Scientific Reports
Induced pluripotent stem cell (iPSC)-derived motor neurons (MNs) offer a promising model system for understanding motor neuron diseases (MNDs) and advancing drug discovery.
Finbar Gaffey, David McCoull, Egle Vaitone, Erin Hedges, Christopher Lovejoy, Zhi Yao, Paul D. Wright, Richard J. Mead, Will Stebbeds   +8 more
doaj   +1 more source

Open Service Innovation in Health Care: What Can We Learn from Open Innovation Communities?

, 2012
The purpose of the chapter is to describe and discuss how principles from open innovation, which are primarily derived from commercial product development, could be applied to open service innovation in non-profit health care organisations.
Edenius, Mats,, Mats Edenius, Christina Keller, Lindblad, Staffan,, Keller, Christina,, Staffan Lindblad   +5 more
core   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro, Freda Qi, Karen Colwill, Alina D. Dorogy, Ying Liu, Michelle Science, Anne‐Claude Gingras, James M. Rini, Sumit Gupta, Sarah Alexander, Shelly Bolotin, Tania H. Watts   +11 more
wiley   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

Cross-modal adaptive reconstruction of open education resources

Scientific Reports
Matching vast online resources to individual learners’ needs remains a major challenge, especially for adults with diverse backgrounds. To address this challenge, we proposed a Dynamic Knowledge Graph-enhanced Cross-Modal Recommendation model (DKG-CMR ...
Tang Shengju, Feng Li, Zhan Wang, Xie Zhaoyuan   +3 more
doaj   +1 more source