Results 21 to 30 of about 2,501,794 (292)

Multispectral imaging via feature selection: A frugal innovation approach for pathogen identification [PDF]

open access: yesEPJ Web of Conferences, 2023
In order to develop an affordable clinical diagnostic instrument for use in more decentralized settings, we have assessed the feasibility to move from hyperspectral to multispectral imaging via parsimonious feature selection.
Leroux Denis   +3 more
doaj   +1 more source

Annexin A5 Increases Survival in Murine Sepsis Model by Inhibiting HMGB1-Mediated Proinflammation and Coagulation

open access: yesMolecular Medicine, 2016
The identification of HMGB1 as a late mediator in sepsis has highlighted HMGB1 as a promising therapeutic target for sepsis treatment. Recent studies have revealed that annexin A5, a 35 kDa Ca2+-dependent phospholipid binding protein, exerts ...
Jung Hwa Park   +10 more
doaj   +1 more source

Open minds, open innovation [PDF]

open access: yesJournal of Intellectual Property Law & Practice, 2011
Not so many years ago, the term “open innovation” was unknown to the intellectual property community. While the concept existed, there was little evidence that it existed, or that it was likely to gain any currency at all, before the publication in 2003 of Henry Chesburgh’s Open Innovation: The new imperative for creating and profiting from technology.
openaire   +1 more source

Wie Crowdsourcing neue Forschungsansätze liefert. "Reden Sie mit!" – Ein Innovationsprojekt der Ludwig Boltzmann Gesellschaft

open access: yesMitteilungen der Vereinigung Österreichischer Bibliothekarinnen und Bibliothekare, 2019
Forschung muss Nutzen stiften, insbesondere vor dem Hintergrund sozialer, ökologischer, wirtschaftlicher und politischer Problemstellungen ist die Wissenschaft gefordert gesellschaftlich relevante Fragestellungen aufzugreifen.
Lucia Malfent, Benjamin Missbach
doaj   +1 more source

One-step preparation of antimicrobial silicone materials based on PDMS and salicylic acid: insights from spatially and temporally resolved techniques

open access: yesnpj Biofilms and Microbiomes, 2021
In this work, we introduce a one-step strategy that is suitable for continuous flow manufacturing of antimicrobial PDMS materials. The process is based on the intrinsic capacity of PDMS to react to certain organic solvents, which enables the ...
Luca Barbieri   +6 more
doaj   +1 more source

Co-creating a patient and public involvement and engagement ‘how to’ guide for researchers

open access: yesResearch Involvement and Engagement, 2020
Plain language summary Research should benefit society at large. Involving citizens those who are affected by research may not only increase the quality, but can also push research towards generating greater societal benefits and relevant outcomes for ...
Raphaela E. Kaisler, Benjamin Missbach
doaj   +1 more source

Engineered adeno-associated virus 3 vector with reduced reactivity to serum antibodies

open access: yesScientific Reports, 2021
The natural serotypes of adeno-associated virus (AAV) or their variants, such as AAV8 and AAV5, are commonly used as vectors in the clinical programs for liver-targeted gene therapy.
Mika Ito   +4 more
doaj   +1 more source

Label-free chemical imaging of cytochrome P450 activity by Raman microscopy

open access: yesCommunications Biology, 2022
Cytochrome P450 activity is assessed at the single-cell level using chemical imaging, Raman microscopy, which gives quantitative insights into effects of drug administration on cellular biochemistry.
Menglu Li   +5 more
doaj   +1 more source

A Taxonomy to Understand Scaling of Innovation by African Enterprises

open access: yesThe African Journal of Information and Communication, 2021
Grounded in empirical research findings and key statements in the literature, this article proposes a four-part taxonomy for mapping African knowledge-based enterprises’ efforts to achieve scale. The taxonomy, adapted from the framework proposed by Uvin
Chris Armstrong, Jeremy De Beer
doaj  

Annexin A5 as an immune checkpoint inhibitor and tumor-homing molecule for cancer treatment

open access: yesNature Communications, 2020
AnnexinV has been shown to bind phosphatidylserine expressed by chemotherapy-induced apoptotic cells increasing their immunogeneicity. Here, the authors demonstrate in a preclinical tumor model that fusing tumor-antigen peptide to Annexin V enhances its ...
Tae Heung Kang   +10 more
doaj   +1 more source

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